Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data (Anti-I-309 antibody, All lanes: Anti-I-309 at 0.5ug/ml Lane 1: U87 Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: COLO320 Whole Cell Lysate at 40ug Predicted band size: 11KD Observed band size: 11KD)

Rabbit anti-Human I-309 Polyclonal Antibody | anti-I-309 antibody

I-309 (C-C Motif Chemokine 1, Ccl1, CCL1_HUMAN, Chemokine CC Motif Ligand 1, Inflammatory Cytokine I-309, P500, SCYA1, SISe, Small Inducible Cytokine A1, Small-inducible Cytokine A1, T Lymphocyte Secreted Protein I-309, T Lymphocyte-secreted Protein I-309

Gene Names
CCL1; P500; SISe; TCA3; I-309; SCYA1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
I-309; Polyclonal Antibody; I-309 (C-C Motif Chemokine 1; Ccl1; CCL1_HUMAN; Chemokine CC Motif Ligand 1; Inflammatory Cytokine I-309; P500; SCYA1; SISe; Small Inducible Cytokine A1; Small-inducible Cytokine A1; T Lymphocyte Secreted Protein I-309; T Lymphocyte-secreted Protein I-309; anti-I-309 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human I-309.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight490.
Applicable Applications for anti-I-309 antibody
Western Blot (WB), FLISA
Application Notes
WB: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions.
FLISA: 0.1-0.5ug/ml
Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to human I-309 expressed in E. coli. (Position: K24-K96). Species sequence homology: mouse (38%)
Conjugate
MaxLight490
Note
Preservative Free
Preparation and Storage
May be stored at -20 degree C. Stable for 12 months after receipt at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

(Anti-I-309 antibody, All lanes: Anti-I-309 at 0.5ug/ml Lane 1: U87 Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: COLO320 Whole Cell Lysate at 40ug Predicted band size: 11KD Observed band size: 11KD)

Testing Data (Anti-I-309 antibody, All lanes: Anti-I-309 at 0.5ug/ml Lane 1: U87 Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: COLO320 Whole Cell Lysate at 40ug Predicted band size: 11KD Observed band size: 11KD)
Product Categories/Family for anti-I-309 antibody
References
1. Miller, M. D., Wilson, S. D., Dorf, M. E., Seuanez, H. N., O'Brien, S. J., Krangel, M. S.Sequence and chromosomal location of the I-309 gene: relationship to genes encoding a family of inflammatory cytokines.J. Immun. 145: 2737-2744, 1990.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,992 Da
NCBI Official Full Name
C-C motif chemokine 1
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 1
NCBI Official Symbol
CCL1
NCBI Official Synonym Symbols
P500; SISe; TCA3; I-309; SCYA1
NCBI Protein Information
C-C motif chemokine 1; T lymphocyte-secreted protein I-309; inflammatory cytokine I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
UniProt Protein Name
C-C motif chemokine 1
UniProt Gene Name
CCL1
UniProt Synonym Gene Names
SCYA1
UniProt Entry Name
CCL1_HUMAN

NCBI Description

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]

Uniprot Description

CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; signal transduction; chemotaxis

Research Articles on I-309

Similar Products

Product Notes

The I-309 ccl1 (Catalog #AAA6460722) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The I-309 (C-C Motif Chemokine 1, Ccl1, CCL1_HUMAN, Chemokine CC Motif Ligand 1, Inflammatory Cytokine I-309, P500, SCYA1, SISe, Small Inducible Cytokine A1, Small-inducible Cytokine A1, T Lymphocyte Secreted Protein I-309, T Lymphocyte-secreted Protein I-309 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's I-309 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions. FLISA: 0.1-0.5ug/ml Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the I-309 ccl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "I-309, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.