Western Blot (WB)
(Western Blot: Sample: Recombinant HYAL2, Mouse.)
Rabbit anti-Mouse Hyaluronoglucosaminidase 2 (HYAL2) Polyclonal Antibody | anti-HYAL2 antibody
Polyclonal Antibody to Hyaluronoglucosaminidase 2 (HYAL2)
MGHHHHHHSGSEF-LKPTAPPI FTGRPFVVAW NVPTQECAPR HKVPLDLRAF DVKATPNEGF FNQNITTFYY DRLGLYPRFD AAGTSVHGGV PQNGSLCAHL PMLKESVERY IQTQEPGGLA VIDWEEWRPV WVRNWQEKDV YRQSSRQLVA SRHPDWPSDR VMKQAQYEFE FAARQFMLNT LRYVKAVRPQ HLWGFYLFPD CYNHDYVQNW ESYTGRCPDV EVARNDQLAW LWAESTALFP SVYLDETLAS SVHSRNFVSF RVREALRVAH THHANHALPV YVFTRPTYTR GLTGLSQVDL ISTIGESAAL GSAGVIFWGD SEDASSMETC QYLKNYLTQL LVPYIVNVSW ATQYCSWTQC HGHGRCVRRN PSANTFLHLN ASSFRLVPGH TPSEPQLRPE GQLSEADLNY LQKHFRCQCY LGWGGEQCQR NYKGAAG
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant HYAL2, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HYAL2, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
NCBI and Uniprot Product Information
Uniprot Description
HYAL2: Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R. Belongs to the glycosyl hydrolase 56 family.
Protein type: EC 3.2.1.35; Glycan Metabolism - glycosaminoglycan degradation; Hydrolase; Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 9 F1|9 58.12 cM
Cellular Component: anchored component of external side of plasma membrane; anchored to plasma membrane; apical plasma membrane; cell surface; cytoplasm; cytoplasmic vesicle; cytosol; endocytic vesicle; Golgi membrane; lysosome; membrane; membrane raft; microvillus; perinuclear region of cytoplasm; plasma membrane
Molecular Function: catalytic activity; enzyme binding; hyaluronic acid binding; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; receptor signaling protein tyrosine kinase inhibitor activity; receptor tyrosine kinase binding; transforming growth factor beta binding; viral receptor activity
Biological Process: carbohydrate metabolic process; defense response to virus; entry of virus into host cell; fusion of virus membrane with host plasma membrane; glycosaminoglycan catabolic process; hemopoietic progenitor cell differentiation; hyaluronan catabolic process; metabolic process; monocyte activation; multicellular organismal aging; negative regulation of cell growth; negative regulation of MAP kinase activity; negative regulation of protein kinase B signaling cascade; positive regulation of inflammatory response; positive regulation of protein import into nucleus; positive regulation of transcription from RNA polymerase II promoter; response to reactive oxygen species; response to virus; skeletal morphogenesis; transformation of host cell by virus
Research Articles on HYAL2
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Product Notes
The HYAL2 hyal2 (Catalog #AAA2005081) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Hyaluronoglucosaminidase 2 (HYAL2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Hyaluronoglucosaminidase 2 (HYAL2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the HYAL2 hyal2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSG SEF-LKPTAP PI FTGRPFVVAW NVPTQECAPR HKVPLDLRAF DVKATPNEGF FNQNITTFYY DRLGLYPRFD AAGTSVHGGV PQNGSLCAHL PMLKESVERY IQTQEPGGLA VIDWEEWRPV WVRNWQEKDV YRQSSRQLVA SRHPDWPSDR VMKQAQYEFE FAARQFMLNT LRYVKAVRPQ HLWGFYLFPD CYNHDYVQNW ESYTGRCPDV EVARNDQLAW LWAESTALFP SVYLDETLAS SVHSRNFVSF RVREALRVAH THHANHALPV YVFTRPTYTR GLTGLSQVDL ISTIGESAAL GSAGVIFWGD SEDASSMETC QYLKNYLTQL LVPYIVNVSW ATQYCSWTQC HGHGRCVRRN PSANTFLHLN ASSFRLVPGH TPSEPQLRPE GQLSEADLNY LQKHFRCQCY LGWGGEQCQR NYKGAAG. It is sometimes possible for the material contained within the vial of "Hyaluronoglucosaminidase 2 (HYAL2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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