Rabbit anti-Human HTR1E Polyclonal Antibody | anti-HTR1E antibody
HTR1E antibody
Gene Names
HTR1E; 5-HT1E
Reactivity
Human
Applications
Immunohistochemistry
Purity
HTR1E antibody was purified by affinity chromatography.
Synonyms
HTR1E; Polyclonal Antibody; HTR1E antibody; Polyclonal HTR1E; Anti-HTR1E; serotonin 1e receptor; 5-ht1e receptor; 5-hydroxytryptamine 1e receptor; ht1e receptor; 5-ht1e; HTRE 1; HTRE -1; htr1e; serotonin 5-ht-1e receptor; anti-HTR1E antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human
Purity/Purification
HTR1E antibody was purified by affinity chromatography.
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
365
Applicable Applications for anti-HTR1E antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 16-24 ug/ml
Biological Significance
5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor). The human gene is denoted as HTR1E. It is hypothesized that the 5-HT1E receptor is involved in the regulation of memory in humans due to the high abundance of receptors in the frontal cortex, hippocampus, and olfactory bulb, all of which are regions of the brain integral to memory regulation.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
HTR1E antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-HTR1E antibody
Rabbit polyclonal HTR1E antibody
Product Categories/Family for anti-HTR1E antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,682 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1E
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
NCBI Official Symbol
HTR1E
NCBI Official Synonym Symbols
5-HT1E
NCBI Protein Information
5-hydroxytryptamine receptor 1E
UniProt Protein Name
5-hydroxytryptamine receptor 1E
Protein Family
UniProt Gene Name
HTR1E
UniProt Synonym Gene Names
5-HT-1E; 5-HT1E
UniProt Entry Name
5HT1E_HUMAN
Uniprot Description
5-HT(1E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q14-q15
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; serotonin binding; serotonin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; negative regulation of cAMP metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway; serotonin receptor signaling pathway
Research Articles on HTR1E
Similar Products
Product Notes
The HTR1E htr1e (Catalog #AAA535468) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HTR1E antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HTR1E can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 16-24 ug/ml. Researchers should empirically determine the suitability of the HTR1E htr1e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTR1E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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