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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using HSPB2 antibody.)

Rabbit HSPB2 Polyclonal Antibody | anti-HSPB2 antibody

HSPB2 antibody

Gene Names
HSPB2; MKBP; HSP27; Hs.78846; LOH11CR1K
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
HSPB2; Polyclonal Antibody; HSPB2 antibody; MKBP; HSP27; Hs.78846; LOH11CR1K; anti-HSPB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total HSPB2 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
182
Applicable Applications for anti-HSPB2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:200
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human HSPB2.
Target Name
HSPB2
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using HSPB2 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using HSPB2 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U20S cell using HSPB2 antibody. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of U20S cell using HSPB2 antibody. Blue: DAPI for nuclear staining.)
Related Product Information for anti-HSPB2 antibody
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.
Product Categories/Family for anti-HSPB2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,233 Da
NCBI Official Full Name
heat shock protein beta-2
NCBI Official Synonym Full Names
heat shock 27kDa protein 2
NCBI Official Symbol
HSPB2
NCBI Official Synonym Symbols
MKBP; HSP27; Hs.78846; LOH11CR1K
NCBI Protein Information
heat shock protein beta-2
UniProt Protein Name
Heat shock protein beta-2
Protein Family
UniProt Gene Name
HSPB2
UniProt Synonym Gene Names
HspB2; MKBP
UniProt Entry Name
HSPB2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012]

Uniprot Description

HSPB2: May regulate the kinase DMPK. Belongs to the small heat shock protein (HSP20) family.

Protein type: Chaperone; Heat shock protein

Chromosomal Location of Human Ortholog: 11q22-q23

Cellular Component: cytoplasm; nucleus; cytosol

Molecular Function: protein binding; enzyme activator activity

Biological Process: positive regulation of catalytic activity; response to unfolded protein

Research Articles on HSPB2

Similar Products

Product Notes

The HSPB2 hspb2 (Catalog #AAA9404482) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HSPB2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HSPB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Western blotting: 1:500 - 1:2000 Immunofluorescence: 1:50 - 1:200. Researchers should empirically determine the suitability of the HSPB2 hspb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSPB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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