Rabbit anti-Human HOXB3 Polyclonal Antibody | anti-HOXB3 antibody

HOXB3, ID (HOXB3, HOX2G, Homeobox protein Hox-B3, Homeobox protein Hox-2.7, Homeobox protein Hox-2G) (Biotin)

Cat. Num. AAA6307827

• Gene Names: HOXB3; HOX2; HOX2G; Hox-2.7
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: HOXB3; Polyclonal Antibody; ID (HOXB3; HOX2G; Homeobox protein Hox-B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G) (Biotin); Homeobox protein Hox-2G; anti-HOXB3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-HOXB3 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: HOXB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-148 amino acids from the Central region of human HOXB3.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HOXB3 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HOXB3 antibody detected the HOXB3 protein (arrow).)

Immunohistochemistry (IHC)

(HOXB3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HOXB3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-HOXB3 antibody

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).

Product Categories/Family for anti-HOXB3 antibody

Antibodies; Transcription Factors; Zinc; Ring; Homeobox

References

Palakurthy, R.K., et al. Mol. Cell 36(2):219-230(2009). Ferrai, C., et al. Mol. Biol. Cell 20(15):3543-3551(2009). Chung, N., et al. Mol. Biol. Rep. 36(2):227-235(2009). Speleman, F., et al. Leukemia 19(3):358-366(2005). Roche, J., et al. Leukemia 18(6):1059-1063(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 84570137
• NCBI GeneID: 3213
• NCBI Accession #: NP_002137.4
• NCBI GenBank Nucleotide #: NM_002146.4
• UniProt Accession #: P14651; O95615; P17484; A8K567; D3DTV3
• Molecular Weight: 44,340 Da
• NCBI Official Full Name: homeobox protein Hox-B3
• NCBI Official Synonym Full Names: homeobox B3
• NCBI Official Symbol: HOXB3
• NCBI Official Synonym Symbols: HOX2; HOX2G; Hox-2.7
• NCBI Protein Information: homeobox protein Hox-B3; homeo box 2G; homeo box B3; homeobox protein Hox-2G; homeobox protein Hox-2.7
• UniProt Protein Name: Homeobox protein Hox-B3
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXB3
• UniProt Synonym Gene Names: HOX2G

NCBI Description

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008]

Uniprot Description

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.