Rabbit anti-Human, mouse Hoxb1 Polyclonal Antibody | anti-Hoxb1 antibody

Mouse Hoxb1 Antibody (C-term)

Cat. Num. AAA9205066

• Gene Names: Hoxb1; Hox-2.9
• Reactivity: Human, mouse
• Applications: Western Blot, ELISA
• Purity: Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: Hoxb1; Polyclonal Antibody; Mouse Hoxb1 Antibody (C-term); Homeobox protein Hox-B1; Homeobox protein Hox-29; Hox-29; Hoxb-1; anti-Hoxb1 antibody

• Host: Rabbit
• Reactivity: Human, mouse
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This Mouse Hoxb1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 182-315 amino acids from the C-terminal region of Mouse Hoxb1.
• Purity/Purification: Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.5 (varies by lot)
• Sequence Length: 297

• Applicable Applications for anti-Hoxb1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB~~1:1000
• Crown Antibody: Yes
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-Hoxb1 Antibody (C-term) at 1:2000 dilution + human skeletal muscle lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 32 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB)

(All lanes : Anti-Hoxb1 Antibody (C-term) at 1:1000 dilutionLane 1: mouse heart lysatesLane 2: mouse liver lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 32 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-Hoxb1 antibody

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.

Product Categories/Family for anti-Hoxb1 antibody

Crown Antibodies

References

Frohman M.A.,et al.Development 110:589-607(1990).
Murphy P.,et al.Development 111:61-74(1991).
Carninci P.,et al.Science 309:1559-1563(2005).
Rubock M.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:4751-4755(1990).

NCBI and Uniprot Product Information

• NCBI GI #: 226693400
• NCBI GeneID: 15407
• NCBI Accession #: NP_032292.3
• NCBI GenBank Nucleotide #: NM_008266.5
• UniProt Accession #: P17919; Q3ZAY6; Q9CYH3
• Molecular Weight: 31672
• NCBI Official Full Name: homeobox protein Hox-B1
• NCBI Official Synonym Full Names: homeobox B1
• NCBI Official Symbol: Hoxb1
• NCBI Official Synonym Symbols: Hox-2.9
• NCBI Protein Information: homeobox protein Hox-B1
• UniProt Protein Name: Homeobox protein Hox-B1
• Protein Family: Homeobox protein
• UniProt Gene Name: Hoxb1
• UniProt Synonym Gene Names: Hox-2.9; Hoxb-1
• UniProt Entry Name: HXB1_MOUSE

Uniprot Description

HOXB1: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Defects in HOXB1 are the cause of facial paresis, hereditary congenital, 3 (HCFP3). A form of facial paresis, a disease characterized by isolated dysfunction of the facial nerve (CN VII). HCFP3 patients are affected by bilateral facial palsy, facial muscle weakness of muscles innervated by CN VII, hearing loss, and strabismus. Belongs to the Antp homeobox family. Labial subfamily.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Cellular Component: nucleus

Molecular Function: protein domain specific binding; DNA binding; sequence-specific DNA binding

Biological Process: facial nerve structural organization; rhombomere development; anatomical structure morphogenesis; facial nucleus development; transcription, DNA-dependent; multicellular organismal development; rhombomere 4 development; embryonic skeletal morphogenesis; anterior/posterior pattern formation; regulation of transcription, DNA-dependent; anatomical structure formation; positive regulation of transcription from RNA polymerase II promoter; rhombomere 5 development