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Western Blot (WB) (Western blot analysis of HOXA5 antibody (C-term E211) in mouse kidney tissue lysates (35ug/lane). HOXA5 (arrow) was detected using the purified Pab.)

Rabbit anti-Human, Mouse Hox A5 Polyclonal Antibody | anti-HOXA5 antibody

Hox A5, CT (Homeobox A5, Homeobox Protein Hox-A5, HOXA5, HOX1, HOX1.3, Homeobox Protein Hox-1C, HOX1C, MGC9376) (MaxLight 650)

Gene Names
HOXA5; HOX1; HOX1C; HOX1.3
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
Hox A5; Polyclonal Antibody; CT (Homeobox A5; Homeobox Protein Hox-A5; HOXA5; HOX1; HOX1.3; Homeobox Protein Hox-1C; HOX1C; MGC9376) (MaxLight 650); anti-HOXA5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human HOXA5. Species Crossreactivity: mouse.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-HOXA5 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human HOXA5 (KLH).
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of HOXA5 antibody (C-term E211) in mouse kidney tissue lysates (35ug/lane). HOXA5 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of HOXA5 antibody (C-term E211) in mouse kidney tissue lysates (35ug/lane). HOXA5 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of 293 cells using HOXA5 Antibody (C-term E211)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of 293 cells using HOXA5 Antibody (C-term E211)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-HOXA5 antibody
References
1. Chen, Y., Blood 111(3), 1217-1226 (2008). 2. Chen, H., Cancer Res. 67(17), 8007-8013 (2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29kDa
NCBI Official Full Name
homeobox protein Hox-A5
NCBI Official Synonym Full Names
homeobox A5
NCBI Official Symbol
HOXA5
NCBI Official Synonym Symbols
HOX1; HOX1C; HOX1.3
NCBI Protein Information
homeobox protein Hox-A5
UniProt Protein Name
Homeobox protein Hox-A5
Protein Family
UniProt Gene Name
HOXA5
UniProt Synonym Gene Names
HOX1C
UniProt Entry Name
HXA5_HUMAN

NCBI Description

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXA5: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'. Belongs to the Antp homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7p15.2

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; transcription factor activity

Biological Process: cell migration; negative regulation of erythrocyte differentiation; positive regulation of myeloid cell differentiation; transcription, DNA-dependent; positive regulation of apoptosis; multicellular organism growth; embryonic skeletal morphogenesis; anterior/posterior pattern formation; regulation of mammary gland epithelial cell proliferation; respiratory system process; negative regulation of angiogenesis; thyroid gland development; positive regulation of transcription from RNA polymerase II promoter; alveolus development

Research Articles on HOXA5

Similar Products

Product Notes

The HOXA5 hoxa5 (Catalog #AAA6481115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Hox A5, CT (Homeobox A5, Homeobox Protein Hox-A5, HOXA5, HOX1, HOX1.3, Homeobox Protein Hox-1C, HOX1C, MGC9376) (MaxLight 650) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Hox A5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HOXA5 hoxa5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hox A5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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