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SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal liver tissue lysate, Primary antibody:HOOK2 Antibody at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Rabbit anti-Human, Mouse HOOK2 Polyclonal Antibody | anti-HOOK2 antibody

HOOK2 Antibody

Gene Names
HOOK2; HK2
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
HOOK2; Polyclonal Antibody; HOOK2 Antibody; HK2; anti-HOOK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.9mg/mL (varies by lot)
Applicable Applications for anti-HOOK2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:1000
IHC: 1:40-1:200
Immunogen
Fusion protein of human HOOK2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal liver tissue lysate, Primary antibody:HOOK2 Antibody at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal liver tissue lysate, Primary antibody:HOOK2 Antibody at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (HOOK2 Antibody) at dilution 1/50.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (HOOK2 Antibody) at dilution 1/50.)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (HOOK2 Antibody) at dilution 1/50.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (HOOK2 Antibody) at dilution 1/50.)
Related Product Information for anti-HOOK2 antibody
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.
Product Categories/Family for anti-HOOK2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
83,022 Da
NCBI Official Full Name
Homo sapiens hook homolog 2 (Drosophila), mRNA
NCBI Official Synonym Full Names
hook microtubule tethering protein 2
NCBI Official Symbol
HOOK2
NCBI Official Synonym Symbols
HK2
NCBI Protein Information
protein Hook homolog 2
UniProt Protein Name
DNA polymerase theta
Protein Family
UniProt Gene Name
POLQ
UniProt Synonym Gene Names
POLH
UniProt Entry Name
DPOLQ_HUMAN

NCBI Description

Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

Uniprot Description

POLQ: Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links. Belongs to the DNA polymerase type-A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage; Transferase; EC 2.7.7.7

Chromosomal Location of Human Ortholog: 3q13.33

Cellular Component: nucleoplasm

Molecular Function: DNA-directed DNA polymerase activity; damaged DNA binding; ATP binding; single-stranded DNA-dependent ATPase activity

Biological Process: DNA repair; DNA-dependent DNA replication

Research Articles on HOOK2

Similar Products

Product Notes

The HOOK2 polq (Catalog #AAA9434811) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HOOK2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's HOOK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1:40-1:200. Researchers should empirically determine the suitability of the HOOK2 polq for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HOOK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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