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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using HNRNPU antibody at 1:3000 dilution.)

Rabbit anti-Human, Rat HNRNPU Polyclonal Antibody | anti-HNRNPU antibody

HNRNPU Polyclonal Antibody

Gene Names
HNRNPU; SAFA; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1
Reactivity
Human, Rat
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
HNRNPU; Polyclonal Antibody; HNRNPU Polyclonal Antibody; heterogeneous nuclear ribonucleoprotein Upp120 p120 nuclear protein scaffold attachment factor A; HNRPU; SAF-A; U21.1; hnRNP U; anti-HNRNPU antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
HNRNPU polyclonal antibody detects endogenous levels of HNRNPU protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
825
Applicable Applications for anti-HNRNPU antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:200
Immunogen
Recombinant protein of human HNRNPU
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using HNRNPU antibody at 1:3000 dilution.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using HNRNPU antibody at 1:3000 dilution.)
Related Product Information for anti-HNRNPU antibody
Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
120kDa
NCBI Official Full Name
Heterogeneous nuclear ribonucleoprotein U
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein U
NCBI Official Symbol
HNRNPU
NCBI Official Synonym Symbols
SAFA; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein U
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein U
UniProt Gene Name
HNRNPU
UniProt Synonym Gene Names
HNRPU; SAFA; U21.1; hnRNP U; SAF-A
UniProt Entry Name
HNRPU_HUMAN

NCBI Description

This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]

Uniprot Description

hnRNP U: Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; Nuclear receptor co-regulator; RNA splicing; DNA-binding; RNA-binding

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: nucleoplasm; cell surface; membrane; ribonucleoprotein complex; nucleus

Molecular Function: protein binding; DNA binding; RNA binding; ATP binding

Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; osteoblast differentiation; RNA splicing; gene expression; circadian regulation of gene expression

Research Articles on HNRNPU

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Product Notes

The HNRNPU hnrnpu (Catalog #AAA3009959) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HNRNPU Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HNRNPU can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the HNRNPU hnrnpu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HNRNPU, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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