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Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, 293 cells and K562 cells, using hnRNP H antibody.)

Rabbit hnRNP H Polyclonal Antibody | anti-hnRNP H antibody

hnRNP H Antibody

Gene Names
HNRNPH2; FTP3; HNRPH'; HNRPH2; hnRNPH'
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
hnRNP H; Polyclonal Antibody; hnRNP H Antibody; FTP-3; FTP3; HNRH2; HNRPH2; Heterogeneous nuclear ribonucleoprotein H'; anti-hnRNP H antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total hnRNP H protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
449
Applicable Applications for anti-hnRNP H antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human hnRNP H.
Target Name
hnRNP H
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells, 293 cells and K562 cells, using hnRNP H antibody.)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, 293 cells and K562 cells, using hnRNP H antibody.)
Related Product Information for anti-hnRNP H antibody
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).Vorechovsky I., Genomics 21:517-524(1994).Ross M.T., Nature 434:325-337(2005).Olsen J.V., Cell 127:635-648(2006).
Product Categories/Family for anti-hnRNP H antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,264 Da
NCBI Official Full Name
heterogeneous nuclear ribonucleoprotein H2
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein H2 (H')
NCBI Official Symbol
HNRNPH2
NCBI Official Synonym Symbols
FTP3; HNRPH'; HNRPH2; hnRNPH'
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein H2
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein H2
UniProt Gene Name
HNRNPH2
UniProt Synonym Gene Names
FTP3; HNRPH2; hnRNP H2; hnRNP H'
UniProt Entry Name
HNRH2_HUMAN

NCBI Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]

Uniprot Description

hnRNP H2: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: nucleoplasm; membrane; ribonucleoprotein complex; nucleus

Molecular Function: RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression

Research Articles on hnRNP H

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Product Notes

The hnRNP H hnrnph2 (Catalog #AAA9409845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The hnRNP H Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's hnRNP H can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the hnRNP H hnrnph2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hnRNP H, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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