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Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cell using HMGN2 antibody.)

Rabbit anti-Human, Rat HMGN2 Polyclonal Antibody | anti-HMGN2 antibody

HMGN2 Polyclonal Antibody

Reactivity
Human, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity Purification
Synonyms
HMGN2; Polyclonal Antibody; HMGN2 Polyclonal Antibody; HMG17; anti-HMGN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence Length
90
Applicable Applications for anti-HMGN2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-100
Immunogen
Recombinant protein of human HMGN2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19073
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cell using HMGN2 antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cell using HMGN2 antibody.)
Related Product Information for anti-HMGN2 antibody
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
Calculated MW: 9kDa
NCBI Official Full Name
HMGN2
UniProt Protein Name
Non-histone chromosomal protein HMG-17
UniProt Gene Name
HMGN2
UniProt Synonym Gene Names
HMG17
UniProt Entry Name
HMGN2_HUMAN

Uniprot Description

HMGN2: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Belongs to the HMGN family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1p36.1

Cellular Component: chromatin; cytoplasm; nucleus

Molecular Function: nucleosomal DNA binding; protein binding

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Product Notes

The HMGN2 hmgn2 (Catalog #AAA2539840) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMGN2 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HMGN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-100. Researchers should empirically determine the suitability of the HMGN2 hmgn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMGN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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