Rabbit HK1/Hexokinase 1 Polyclonal Antibody | anti-HK1 antibody

Anti-HK1/Hexokinase 1 Antibody (C-Terminus)

Cat. Num. AAA2401406

• Gene Names: HK1; HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase
• Reactivity: Human; Predicted: Mouse, Rat
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: HK1/Hexokinase 1; Polyclonal Antibody; Anti-HK1/Hexokinase 1 Antibody (C-Terminus); Mouse Monoclonal [clone 4D7] (IgG2a; k) to Human HK1/Hexokinase 1; HK1; Brain form hexokinase; Hexokinase 1; Hexokinase type I; HK I; HK1-tb; HK1-tc; HKI; Hexokinase type 1; HK1-ta; HXK1; Glycolytic enzyme; Hexokinase-1; Type 1 hexokinase; Type i hexokinase; anti-HK1 antibody

• Host: Rabbit
• Reactivity: Human; Predicted: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Sequence Length: 917

• Applicable Applications for anti-HK1 antibody: ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IF: 20 ug/ml; IHC-P: 10 ug/ml; WB: 1-2 ug/ml
• Conjugation: Unconjugated
• Epitope: C-Terminus
• Preparation and Storage: Store at 4 degree C for three months; Store at -20 degree C and it will be stable for up to one year.; Avoid repeated freeze thaw cycles.

Immunohistochemistry (IHC)

(Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE))

Related Product Information for anti-HK1 antibody

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes aubiquitous form of hexokinase which localizes to the outer membrane ofmitochondria. Mutations in this gene have been associated with hemolyticanemia due to hexokinase deficiency. Alternative splicing of this generesults in five transcript variants which encode different isoforms, some of which are tissue-specific.

Product Categories/Family for anti-HK1 antibody

Non-Protein Kinase; Hexokinase

NCBI and Uniprot Product Information

• NCBI GI #: 188497754
• NCBI GeneID: 3098
• NCBI Accession #: NP_000179.2
• NCBI GenBank Nucleotide #: NM_000188.2
• UniProt Accession #: P19367; O43443; O43444; O75574; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5; E9PCK0
• Molecular Weight: 101,085 Da
• NCBI Official Full Name: hexokinase-1 isoform HKI
• NCBI Official Synonym Full Names: hexokinase 1
• NCBI Official Symbol: HK1
• NCBI Official Synonym Symbols: HK; HKD; HKI; HXK1; RP79; HMSNR; HK1-ta; HK1-tb; HK1-tc; hexokinase
• NCBI Protein Information: hexokinase-1
• UniProt Protein Name: Hexokinase-1
• Protein Family: Probable histidine kinase
• UniProt Gene Name: HK1
• UniProt Synonym Gene Names: HK I

NCBI Description

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]

Uniprot Description

MiscellaneousIn vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).