Western Blot (WB)
(HIST2H2BE Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HIST2H2BE antibody detected the HIST2H2BE protein (arrow).)
Rabbit anti-Human HIST2H2BE Polyclonal Antibody | anti-HIST2H2BE antibody
HIST2H2BE, NT (HIST2H2BE, H2BFQ, Histone H2B type 2-E, Histone H2B-GL105, Histone H2B.q)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(HIST2H2BE Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HIST2H2BE antibody detected the HIST2H2BE protein (arrow).)
Western Blot (WB)
(HIST2H2BE Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HIST2H2BE antibody detected the HIST2H2BE protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]
Uniprot Description
H2B2E: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2B family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: nucleoplasm; extracellular space; nucleosome; nucleus
Molecular Function: DNA binding; protein heterodimerization activity
Biological Process: nucleosome assembly; establishment and/or maintenance of chromatin architecture; defense response to Gram-positive bacterium; innate immune response in mucosa; antibacterial humoral response
Research Articles on HIST2H2BE
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Product Notes
The HIST2H2BE hist2h2be (Catalog #AAA6006499) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HIST2H2BE, NT (HIST2H2BE, H2BFQ, Histone H2B type 2-E, Histone H2B-GL105, Histone H2B.q) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HIST2H2BE can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the HIST2H2BE hist2h2be for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIST2H2BE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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