Western Blot (WB)
((1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat HIP14/ZDHHC17 Polyclonal Antibody | anti-ZDHHC17 antibody
Goat anti-HIP14/ZDHHC17 Antibody
Western Blot: Approx 70kDa band observed in Human and Mouse Brain lysates (calculated MW of 72.7kDa according to NP_056151.1). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
Uniprot Description
HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.
Protein type: Transferase; Tumor suppressor; Membrane protein, integral; Membrane protein, multi-pass; EC 2.3.1.225
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane; integral to membrane; intracellular membrane-bound organelle
Molecular Function: identical protein binding; magnesium ion transmembrane transporter activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoleyltransferase activity; signal transducer activity; zinc ion binding
Biological Process: lipoprotein transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation; signal transduction
Research Articles on ZDHHC17
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Product Notes
The ZDHHC17 zdhhc17 (Catalog #AAA420936) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-HIP14/ZDHHC17 Antibody reacts with Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's HIP14/ZDHHC17 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Approx 70kDa band observed in Human and Mouse Brain lysates (calculated MW of 72.7kDa according to NP_056151.1). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the ZDHHC17 zdhhc17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CYDQISGSGY QLV. It is sometimes possible for the material contained within the vial of "HIP14/ZDHHC17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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