Rabbit anti-Human HINFP Polyclonal Antibody | anti-Hinfp antibody

HINFP, ID (HINFP, MIZF, ZNF743, Histone H4 transcription factor, Histone nuclear factor P, MBD2-interacting zinc finger protein, Methyl-CpG-binding protein 2-interacting zinc finger protein)

Cat. Num. AAA649931

• Gene Names: Hinfp; Mizf; HiNF-P; AA589481
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: HINFP; Polyclonal Antibody; ID (HINFP; MIZF; ZNF743; Histone H4 transcription factor; Histone nuclear factor P; MBD2-interacting zinc finger protein; Methyl-CpG-binding protein 2-interacting zinc finger protein); Anti -HINFP; anti-Hinfp antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-Hinfp antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: HINFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-346 amino acids from the Central region of human HINFP.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HINFP Antibody (Center) western blot analysis in 293 cell line,human placenta,mouse brain and spleen tissue lysates (35ug/lane).This demonstrates the HINFP antibody detected the HINFP protein (arrow).)

Related Product Information for anti-Hinfp antibody

MIZF interacts with methyl-CpG-binding protein-2 (MBD2; MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.

Product Categories/Family for anti-Hinfp antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 281306720
• NCBI GeneID: 102423
• NCBI Accession #: NP_751894.2
• NCBI GenBank Nucleotide #: NM_172162.3
• UniProt Accession #: Q8K1K9; Q8BWY0; E9QPQ4
• Molecular Weight: 58,076 Da
• NCBI Official Full Name: histone H4 transcription factor
• NCBI Official Synonym Full Names: histone H4 transcription factor
• NCBI Official Symbol: Hinfp
• NCBI Official Synonym Symbols: Mizf; HiNF-P; AA589481
• NCBI Protein Information: histone H4 transcription factor; histone nuclear factor P; MBD2-interacting zinc finger protein; methyl-CpG-binding protein 2-interacting zinc finger protein; MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein
• UniProt Protein Name: Histone H4 transcription factor
• Protein Family: Histone H4 transcription factor
• UniProt Gene Name: Hinfp
• UniProt Synonym Gene Names: Mizf; HiNF-P
• UniProt Entry Name: HINFP_MOUSE

Uniprot Description

Function: Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. Ref.4

Subunit structure: Binds MBD2 and a histone deacetylase complex. Interacts with NPAT

By similarity.

Subcellular location: Nucleus

By similarity. Note: Associated with discrete nuclear foci

By similarity.

Post-translational modification: Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation

By similarity.

Sequence similarities: Contains 9 C2H2-type zinc fingers.