Western Blot (WB)
(Western Blot: Sample: Lane1: Human Jurkat Cells; Lane2: Human K562 Cells; Lane3: Human HL-60 Cells; Lane4: Human Hela Cells.)
Rabbit anti-Human High Mobility Group Protein 17 Polyclonal Antibody | anti-HMG17 antibody
Polyclonal Antibody to High Mobility Group Protein 17 (HMG17)
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Jurkat Cells; Lane2: Human K562 Cells; Lane3: Human HL-60 Cells; Lane4: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Jurkat Cells; Lane2: Human K562 Cells; Lane3: Human HL-60 Cells; Lane4: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMG17, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMG17, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Cancer Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Cancer Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Skin Cancer Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Skin Cancer Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]
Uniprot Description
HMGN2: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Belongs to the HMGN family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component: chromatin; cytoplasm; extracellular space; nucleus
Molecular Function: nucleosomal DNA binding; protein binding; RNA binding
Biological Process: antimicrobial humoral immune response mediated by antimicrobial peptide; killing of cells of other organism
Research Articles on HMG17
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Product Notes
The HMG17 hmgn2 (Catalog #AAA2026497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to High Mobility Group Protein 17 (HMG17) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's High Mobility Group Protein 17 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the HMG17 hmgn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "High Mobility Group Protein 17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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