Western Blot (WB)
(Western Blot: Sample: Lane1: Human HepG2 Cells; Lane2: Human Hela Cells.)
Rabbit anti-Human High Mobility Group Nucleosome Binding Domain Protein 1 Polyclonal Antibody | anti-HMGN1 antibody
Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- KEEPKRR SARLSAKPPA KVEAKPKKAA AKDKSSDKKV QTKGKRGAKG KQAEVANQET KEDLPAENGE TKTEESPASD
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human HepG2 Cells; Lane2: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human HepG2 Cells; Lane2: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMGN1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HMGN1, Human.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Ovary tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Ovary tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]
Uniprot Description
HMGN1: a nonhistone chromosomal protein of the HMG-14/HMG-17 protein family. Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
Protein type: DNA-binding; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 21q22.2
Cellular Component: chromatin; cytoplasm; nucleoplasm; nucleus
Molecular Function: DNA binding; nucleosomal DNA binding
Biological Process: chromatin organization; positive regulation of NAD+ ADP-ribosyltransferase activity; positive regulation of RNA elongation; post-embryonic camera-type eye morphogenesis; pyrimidine dimer repair via nucleotide-excision repair; regulation of development, heterochronic; regulation of epithelial cell proliferation; regulation of transcription from RNA polymerase II promoter; response to UV-B; response to UV-C; transcription-coupled nucleotide-excision repair
Research Articles on HMGN1
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Product Notes
The HMGN1 hmgn1 (Catalog #AAA2026955) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's High Mobility Group Nucleosome Binding Domain Protein 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the HMGN1 hmgn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- KEEPKRR SARLSAKPPA KVEAKPKKAA AKDKSSDKKV QTKGKRGAKG KQAEVANQET KEDLPAENGE TKTEESPASD. It is sometimes possible for the material contained within the vial of "High Mobility Group Nucleosome Binding Domain Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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