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Immunohistochemistry (IHC) (Anti-HEPACAM2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit anti-Human HEPACAM2 Polyclonal Antibody | anti-HEPACAM2 antibody

Rabbit Polyclonal to Human HEPACAM2

Gene Names
HEPACAM2; MIKI
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
HEPACAM2; Polyclonal Antibody; Rabbit Polyclonal to Human HEPACAM2; Anti-HEPACAM2 Antibody (C-Terminus) IHC-plus; HEPACAM family member 2; MIKI; Mitotic kinetics regulator; Human HEPACAM2; anti-HEPACAM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human HEPACAM2. HEPACAM2 antibody is human, mouse and rat reactive. At least two isoforms of HEPACAM2 are known to exist; this antibody will detect both isoforms. HEPACAM2 antibody is predicted to not cross-react with HEPACAM.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
462
Applicable Applications for anti-HEPACAM2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: HEPACAM2 antibody can be used for detection of HEPACAM2 by Western blot at 0.5-1 ug/mL.
Target Species
Human
Immunogen Description
A 19 amino acid peptide near the carboxy terminus of human HEPACAM2.
Immunogen Type
Synthetic peptide
Immunogen
HEPACAM2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HEPACAM2.
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-HEPACAM2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-HEPACAM2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Western Blot (WB)

(Western blot analysis of HEPACAM2 in mouse brain tissue lysate with HEPACAM2 antibody at (A) 0.5 ug/ml and (B) 1 ug/ml.)

Western Blot (WB) (Western blot analysis of HEPACAM2 in mouse brain tissue lysate with HEPACAM2 antibody at (A) 0.5 ug/ml and (B) 1 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,115 Da
NCBI Official Full Name
HEPACAM family member 2 isoform 1
NCBI Official Synonym Full Names
HEPACAM family member 2
NCBI Official Symbol
HEPACAM2
NCBI Official Synonym Symbols
MIKI
NCBI Protein Information
HEPACAM family member 2; mitotic kinetics regulator
UniProt Protein Name
HEPACAM family member 2
Protein Family
UniProt Gene Name
HEPACAM2
UniProt Synonym Gene Names
MIKI
UniProt Entry Name
HECA2_HUMAN

Uniprot Description

HEPACAM2: Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q21.3

Cellular Component: Golgi membrane; Golgi apparatus; centrosome; integral to membrane; spindle; midbody

Molecular Function: protein binding

Biological Process: mitosis; cell division; centrosome organization and biogenesis

Research Articles on HEPACAM2

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Product Notes

The HEPACAM2 hepacam2 (Catalog #AAA248164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human HEPACAM2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HEPACAM2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml) Usage: HEPACAM2 antibody can be used for detection of HEPACAM2 by Western blot at 0.5-1 ug/mL. Researchers should empirically determine the suitability of the HEPACAM2 hepacam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HEPACAM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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