Western Blot (WB)
(Western Blot (WB) analysis of HEATR1 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate)
Rabbit HEATR1 Polyclonal Antibody | anti-HEATR1 antibody
HEATR1 Polyclonal Antibody
Gene Names
HEATR1; BAP28; UTP10
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
HEATR1; Polyclonal Antibody; HEATR1 Polyclonal Antibody; HEAT repeat-containing protein 1; Protein BAP28; N-terminally processed; BAP28; anti-HEATR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
HEATR1 polyclonal antibody detects endogenous levels of HEATR1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
2144
Applicable Applications for anti-HEATR1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human HEATR1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of HEATR1 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of HEATR1 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate)
Related Product Information for anti-HEATR1 antibody
HEATR1 (HEAT repeat containing 1), also known as BAP28, is a 2, 144 amino acid nuclear protein involved in nucleolar processing of pre-18S ribosomal RNA. HEATR1 is a member of the HEATR1/UTP10 family and contains one HEAT repeat. The gene encoding HEATR1 is located on human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 242kDa
NCBI Official Full Name
HEAT repeat-containing protein 1
NCBI Official Synonym Full Names
HEAT repeat containing 1
NCBI Official Symbol
HEATR1
NCBI Official Synonym Symbols
BAP28; UTP10
NCBI Protein Information
HEAT repeat-containing protein 1
UniProt Protein Name
HEAT repeat-containing protein 1
Protein Family
UniProt Gene Name
HEATR1
UniProt Synonym Gene Names
BAP28
UniProt Entry Name
HEAT1_HUMAN
Uniprot Description
BAP28: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis. Belongs to the HEATR1/UTP10 family.
Protein type: Nucleolus; Unknown function
Chromosomal Location of Human Ortholog: 1q43
Cellular Component: small subunit processome; mitochondrion; membrane; nucleolus; nucleus
Molecular Function: snoRNA binding; protein binding
Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of transcription from RNA polymerase I promoter
Research Articles on HEATR1
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Product Notes
The HEATR1 heatr1 (Catalog #AAA3007064) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HEATR1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HEATR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the HEATR1 heatr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HEATR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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