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Western Blot (WB) (Western blot analysis of lysates from Jurkat cells, using HCN2 Antibody. The lane on the right is blocked with the synthesized peptide.)

Rabbit HCN2 Polyclonal Antibody | anti-HCN2 antibody

HCN2 Antibody

Gene Names
HCN2; BCNG2; HAC-1; BCNG-2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
HCN2; Polyclonal Antibody; HCN2 Antibody; anti-HCN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
HCN2 Antibody detects endogenous levels of total HCN2 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
889
Applicable Applications for anti-HCN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human HCN2.
Immunogen Range
491-540
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from Jurkat cells, using HCN2 Antibody. The lane on the right is blocked with the synthesized peptide.)

Western Blot (WB) (Western blot analysis of lysates from Jurkat cells, using HCN2 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
610
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
96 kDa
NCBI Official Full Name
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
NCBI Official Synonym Full Names
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
NCBI Official Symbol
HCN2
NCBI Official Synonym Symbols
BCNG2; HAC-1; BCNG-2
NCBI Protein Information
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
UniProt Protein Name
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
UniProt Gene Name
HCN2
UniProt Synonym Gene Names
BCNG2; BCNG-2

NCBI Description

The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]

Uniprot Description

Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages ().

Research Articles on HCN2

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Product Notes

The HCN2 hcn2 (Catalog #AAA9506720) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HCN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HCN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the HCN2 hcn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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