Western Blot (WB)
(HCFC1R1 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the HCFC1R1 antibody detected the HCFC1R1 protein (arrow).)
Rabbit anti-Human HCFC1R1 Polyclonal Antibody | anti-HCFC1R1 antibody
HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1 beta-propeller-interacting protein) (AP)
Gene Names
HCFC1R1; HPIP
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
HCFC1R1; Polyclonal Antibody; NT (HCFC1R1; HPIP; Host cell factor C1 regulator 1; HCF-1 beta-propeller-interacting protein) (AP); HCF-1 beta-propeller-interacting protein; anti-HCFC1R1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Sequence Length
138
Applicable Applications for anti-HCFC1R1 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
HCFC1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HCFC1R1.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(HCFC1R1 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the HCFC1R1 antibody detected the HCFC1R1 protein (arrow).)
Western Blot (WB)
(HCFC1R1 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the HCFC1R1 antibody detected the HCFC1R1 protein (arrow).)
Immunohistochemistry (IHC)
(HCFC1R1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HCFC1R1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(HCFC1R1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HCFC1R1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-HCFC1R1 antibody
Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
Product Categories/Family for anti-HCFC1R1 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Lamesch, P., et al. Genomics 89(3):307-315(2007). Mahajan, S.S., et al. J. Biol. Chem. 277(46):44292-44299(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
host cell factor C1 regulator 1 isoform 1
NCBI Official Synonym Full Names
host cell factor C1 regulator 1
NCBI Official Symbol
HCFC1R1
NCBI Official Synonym Symbols
HPIP
NCBI Protein Information
host cell factor C1 regulator 1
UniProt Protein Name
Host cell factor C1 regulator 1
Protein Family
UniProt Gene Name
HCFC1R1
UniProt Synonym Gene Names
HPIP
UniProt Entry Name
HPIP_HUMAN
Uniprot Description
Function: Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. Ref.1
Subunit structure: Interacts with HCFC1. Ref.1
Subcellular location: Cytoplasm. Nucleus. Note: Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. Ref.1
Tissue specificity: Widely expressed. Ref.1
Research Articles on HCFC1R1
Similar Products
Product Notes
The HCFC1R1 hcfc1r1 (Catalog #AAA6305680) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HCFC1R1, NT (HCFC1R1, HPIP, Host cell factor C1 regulator 1, HCF-1 beta-propeller-interacting protein) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HCFC1R1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-50 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HCFC1R1 hcfc1r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCFC1R1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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