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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using HAS3 antibody.)

Rabbit anti-Human HAS3  Polyclonal Antibody | anti-HAS3  antibody

HAS3  Polyclonal Antibody

Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
HAS3 ; Polyclonal Antibody; HAS3  Polyclonal Antibody; anti-HAS3  antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Applicable Applications for anti-HAS3  antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000, IHC: 1:50-1:200
Immunogen
Recombinant protein of human HAS3
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34204 / sc-34202 / sc-66917
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using HAS3 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using HAS3 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cell using HAS3 antibody. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of A549 cell using HAS3 antibody. Blue: DAPI for nuclear staining.)
Related Product Information for anti-HAS3  antibody
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 62kDa
NCBI Official Full Name
hyaluronan synthase 3 isoform a
NCBI Official Synonym Full Names
hyaluronan synthase 3
NCBI Official Symbol
HAS3
NCBI Protein Information
hyaluronan synthase 3
UniProt Protein Name
Hyaluronan synthase 3
UniProt Gene Name
HAS3
UniProt Synonym Gene Names
HA synthase 3
UniProt Entry Name
HYAS3_HUMAN

NCBI Description

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Uniprot Description

HAS3: Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Belongs to the NodC/HAS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transferase; Motility/polarity/chemotaxis; Membrane protein, integral; EC 2.4.1.212

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: hyaluronan synthase activity

Biological Process: carbohydrate metabolic process; cell adhesion; extracellular polysaccharide biosynthetic process; glycosaminoglycan metabolic process; hyaluronan biosynthetic process; hyaluronan metabolic process; positive regulation of transcription, DNA-dependent

Research Articles on HAS3 

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Product Notes

The HAS3  has3 (Catalog #AAA2535958) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HAS3  Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HAS3  can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000, IHC: 1:50-1:200. Researchers should empirically determine the suitability of the HAS3  has3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAS3 , Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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