Rabbit HADHB Polyclonal Antibody | anti-HADHB antibody

Anti-HADHB Antibody

Cat. Num. AAA2401943

• Gene Names: HADHB; ECHB; MTPB; MSTP029; TP-BETA
• Reactivity: Human; Predicted: Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: HADHB; Polyclonal Antibody; Anti-HADHB Antibody; Rabbit Polyclonal (IgG) to Human HADHB; Acetyl-CoA acyltransferase; Beta-ketothiolase; ECHB; MTPB; MSTP029; TP-BETA; anti-HADHB antibody

• Host: Rabbit
• Reactivity: Human; Predicted: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human HADHB
• Purity/Purification: Affinity Purified
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
• Sequence Length: 474

• Applicable Applications for anti-HADHB antibody: Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IF: 1:10-1:100; IHC: 1:50-1:200; IHC-P: 1:100; WB: 1:500-1:2000
• Immunogen: Recombinant protein of human HADHB
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cells.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using HADHB antibody.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines.)

Related Product Information for anti-HADHB antibody

HADHB encodes the beta subunit of the mitochondrial trifunctionalprotein, which catalyzes the last three steps of mitochondrialbeta-oxidation of long chain fatty acids. the mitochondrialmembrane-bound heterocomplex is composed of four alpha and four betasubunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolaseactivity. the encoded protein can also bind RNA and decreases the stability of some mRNAs.

NCBI and Uniprot Product Information

• NCBI GI #: 4504327
• NCBI GeneID: 3032
• NCBI Accession #: NP_000174.1
• NCBI GenBank Nucleotide #: NM_000183.2
• UniProt Accession #: P55084; O14969; Q53TA6; Q96C77; Q9H3F5; Q9T2V8; B2RB16; B4E2W0
• Molecular Weight: 48,880 Da
• NCBI Official Full Name: trifunctional enzyme subunit beta, mitochondrial isoform 1
• NCBI Official Synonym Full Names: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
• NCBI Official Symbol: HADHB
• NCBI Official Synonym Symbols: ECHB; MTPB; MSTP029; TP-BETA
• NCBI Protein Information: trifunctional enzyme subunit beta, mitochondrial
• UniProt Protein Name: Trifunctional enzyme subunit beta, mitochondrial
• Protein Family: Trifunctional enzyme
• UniProt Gene Name: HADHB

NCBI Description

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]