Western Blot (WB)
(H2BFWT Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the H2BFWT antibody detected the H2BFWT protein (arrow).)
Rabbit anti-Human H2BFWT Polyclonal Antibody | anti-H2BFWT antibody
H2BFWT Antibody (Center)
Western Blot (WB)
(H2BFWT Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the H2BFWT antibody detected the H2BFWT protein (arrow).)
Western Blot (WB)
(H2BFWT Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the H2BFWT antibody detected the H2BFWT protein (arrow).)
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene encodes a member of the H2B histone family
that is specifically expressed in sperm nuclei. A polymorphism in
the 5' UTR of this gene is associated with male infertility.
Boulard, M., et al. Mol. Cell. Biol. 26(4):1518-1526(2006)
Churikov, D., et al. Genomics 84(4):745-756(2004)
Churikov, D., et al. Cytogenet. Genome Res. 105 (2-4), 203-214 (2004) :
NCBI and Uniprot Product Information
NCBI Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Jan 2010]
Uniprot Description
H2BFWT: Atypical histone H2B. Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B. However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes. May be important for telomere function. Belongs to the histone H2B family.
Chromosomal Location of Human Ortholog: Xq22.2
Cellular Component: nuclear membrane; nucleosome
Molecular Function: DNA binding; protein heterodimerization activity
Research Articles on H2BFWT
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Product Notes
The H2BFWT h2bfwt (Catalog #AAA9209591) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 62-88. The H2BFWT Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's H2BFWT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the H2BFWT h2bfwt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "H2BFWT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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