Western Blot (WB)
(Western Blot analysis of H2AJ in Jurkat cell lysate using H2AJ Rabbit pAb at dilution 1/800)
Rabbit H2AJ Polyclonal Antibody | anti-H2AJ antibody
H2AJ Rabbit pAb
IHC-P: 1:200-1:300
Western Blot (WB)
(Western Blot analysis of H2AJ in Jurkat cell lysate using H2AJ Rabbit pAb at dilution 1/800)
Western Blot (WB)
(Western Blot analysis of H2AJ in Jurkat cell lysate using H2AJ Rabbit pAb at dilution 1/800)
Immunohistochemistry (IHC)
(Immunohistochemistry of H2AJ in paraffin-embedded Human esophagus cancer tissue using H2AJ Rabbit pAb at dilution 1/170. Predicted cell location: Nucleus)
Immunohistochemistry (IHC)
(Immunohistochemistry of H2AJ in paraffin-embedded Human esophagus cancer tissue using H2AJ Rabbit pAb at dilution 1/170. Predicted cell location: Nucleus)
NCBI and Uniprot Product Information
Uniprot Description
H2AFJ: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: nucleosome; nucleus
Molecular Function: DNA binding; protein heterodimerization activity
Similar Products
Product Notes
The H2AJ h2afj (Catalog #AAA4759346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The H2AJ Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's H2AJ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:200-1:300. Researchers should empirically determine the suitability of the H2AJ h2afj for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "H2AJ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
