Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using GYPB antibody.)
Rabbit anti-Human GYPB Polyclonal Antibody | anti-GYPB antibody
GYPB Polyclonal Antibody
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using GYPB antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using GYPB antibody.)
NCBI and Uniprot Product Information
NCBI Description
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Uniprot Description
GYPB: This protein is a minor sialoglycoprotein in erythrocyte membranes. Belongs to the glycophorin-A family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q31.21
Cellular Component: integral component of plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: leukocyte migration
Disease: Malaria, Susceptibility To
Research Articles on GYPB
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Product Notes
The GYPB gypb (Catalog #AAA9432409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GYPB Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GYPB can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-1:200. Researchers should empirically determine the suitability of the GYPB gypb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GYPB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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