Western Blot (WB)
(GUCA2A Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GUCA2A antibody detected the GUCA2A protein (arrow).)
Rabbit anti-Human GUCA2A Polyclonal Antibody | anti-GUCA2A antibody
GUCA2A Antibody (Center)
Gene Names
GUCA2A; GUCA2; STARA; GCAP-I
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GUCA2A; Polyclonal Antibody; GUCA2A Antibody (Center); Guanylin; Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Guanylate cyclase-activating protein I; GCAP-I; HMW-guanylin; GUCA2; anti-GUCA2A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.48 (varies by lot)
Sequence Positions
25-54
Sequence Length
115
Applicable Applications for anti-GUCA2A antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(GUCA2A Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GUCA2A antibody detected the GUCA2A protein (arrow).)
Western Blot (WB)
(GUCA2A Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GUCA2A antibody detected the GUCA2A protein (arrow).)
Related Product Information for anti-GUCA2A antibody
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Product Categories/Family for anti-GUCA2A antibody
References
Dell'Orco, D., et al. Cell. Mol. Life Sci. 67(6):973-984(2010)
Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(5):515-517(2009)
Albano, F., et al. Pediatr. Res. 58(1):159-163(2005)
Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)
Kulaksiz, H., et al. Gastroenterology 126(3):732-740(2004)
Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(5):515-517(2009)
Albano, F., et al. Pediatr. Res. 58(1):159-163(2005)
Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)
Kulaksiz, H., et al. Gastroenterology 126(3):732-740(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12388
NCBI Official Full Name
guanylin
NCBI Official Synonym Full Names
guanylate cyclase activator 2A (guanylin)
NCBI Official Symbol
GUCA2A
NCBI Official Synonym Symbols
GUCA2; STARA; GCAP-I
NCBI Protein Information
guanylin
UniProt Protein Name
Guanylin
Protein Family
UniProt Gene Name
GUCA2A
UniProt Synonym Gene Names
GUCA2; GCAP-I
UniProt Entry Name
GUC2A_HUMAN
Uniprot Description
GUCA2A: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. Belongs to the guanylin family.
Protein type: Secreted; Secreted, signal peptide; Activator
Chromosomal Location of Human Ortholog: 1p35-p34
Cellular Component: extracellular region
Molecular Function: hormone activity; guanylate cyclase activator activity
Biological Process: positive regulation of guanylate cyclase activity
Research Articles on GUCA2A
Similar Products
Product Notes
The GUCA2A guca2a (Catalog #AAA9205006) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-54. The GUCA2A Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GUCA2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GUCA2A guca2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GUCA2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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