Rabbit anti-Human Guanylate-binding protein 3 Polyclonal Antibody | anti-GBP3 antibody

Guanylate-binding protein 3 antibody

Cat. Num. AAA9410358

• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: Guanylate-binding protein 3; Polyclonal Antibody; Guanylate-binding protein 3 antibody; anti-GBP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 595

• Applicable Applications for anti-GBP3 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500-1:3000; Immunohistochemistry: 1:100-1:500; Immunofluorescence: 1:100-1:200
• Immunogen Type: Recombinant protein
• Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 61 and 287 of Guanylate-binding protein 3
• Target Name: Guanylate-binding protein 3
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE Primary antibody diluted at 1: 1000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using Guanylate-binding protein 3 antibody at 1: 100 dilution.)

Immunofluorescence (IF)

(Immunofluorescence analysis of methanol-fixed HeLa, using Guanylate binding protein 3 antibody at 1: 200 dilution.)

Related Product Information for anti-GBP3 antibody

This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. [provided by RefSeq]

Product Categories/Family for anti-GBP3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 112382372
• NCBI GeneID: 2635
• NCBI Accession #: NP_060754
• NCBI GenBank Nucleotide #: NM_018284.2
• Molecular Weight: 61,928 Da
• NCBI Official Full Name: guanylate-binding protein 3
• NCBI Official Synonym Full Names: guanylate binding protein 3
• NCBI Official Symbol: GBP3
• NCBI Protein Information: guanylate-binding protein 3
• UniProt Protein Name: Guanylate-binding protein 3
• Protein Family: Guanylate-binding protein
• UniProt Gene Name: GBP3
• UniProt Synonym Gene Names: GBP-3
• UniProt Entry Name: GBP3_HUMAN

NCBI Description

This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. [provided by RefSeq, Jul 2008]

Uniprot Description

GBP3: Exhibits antiviral activity against influenza virus. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Hydrolase

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: membrane; cytoplasm

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: metabolic process; defense response to virus