Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using GTPBP4 antibody.)
Rabbit anti-Human, Mouse GTPBP4 Polyclonal Antibody | anti-GTPBP4 antibody
GTPBP4 Polyclonal Antibody
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using GTPBP4 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using GTPBP4 antibody.)
NCBI and Uniprot Product Information
NCBI Description
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]
Uniprot Description
GTPBP4: Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the GTP1/OBG family. NOG subfamily.
Protein type: Nucleolus; RNA-binding; Ribosomal
Chromosomal Location of Human Ortholog: 10p15-p14
Cellular Component: cytoplasm; Golgi apparatus; membrane; nuclear membrane; nucleolus; nucleus; perinuclear region of cytoplasm
Molecular Function: GTP binding; GTPase activity; protein binding
Biological Process: negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of collagen binding; negative regulation of DNA replication; negative regulation of protein ubiquitination; osteoblast differentiation; protein stabilization; regulation of cyclin-dependent protein kinase activity
Research Articles on GTPBP4
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Product Notes
The GTPBP4 gtpbp4 (Catalog #AAA2540934) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GTPBP4 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GTPBP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000 - 1:2000. Researchers should empirically determine the suitability of the GTPBP4 gtpbp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTPBP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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