Rabbit anti-Human GTPBP3 Polyclonal Antibody | anti-GTPBP3 antibody

GTPBP3, ID (GTPBP3, MTGP1, tRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1) (PE)

Cat. Num. AAA6305019

• Gene Names: GTPBP3; MSS1; MTGP1; THDF1; GTPBG3; COXPD23
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GTPBP3; Polyclonal Antibody; ID (GTPBP3; MTGP1; tRNA modification GTPase GTPBP3; mitochondrial; GTP-binding protein 3; Mitochondrial GTP-binding protein 1) (PE); mitochondrial GTP-binding protein 1; anti-GTPBP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 492

• Applicable Applications for anti-GTPBP3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GTPBP3 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GTPBP3 antibody detected the GTPBP3 protein (arrow).)

Related Product Information for anti-GTPBP3 antibody

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Product Categories/Family for anti-GTPBP3 antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

References

Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009). Villarroya, M., et al. Mol. Cell. Biol. 28(24):7514-7531(2008). Bykhovskaya, Y., et al. Mol. Genet. Metab. 83(3):199-206(2004). Li, X., et al. Biochem. Biophys. Res. Commun. 312(3):747-754(2003). Li, X., et al. Mol. Cell. Biol. 22(21):7701-7711(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 193082991
• NCBI GeneID: 84705
• NCBI Accession #: NP_116009.2
• NCBI GenBank Nucleotide #: NP_116009.2
• UniProt Accession #: Q969Y2
• NCBI Official Full Name: tRNA modification GTPase GTPBP3, mitochondrial isoform V
• NCBI Official Synonym Full Names: GTP binding protein 3, mitochondrial
• NCBI Official Symbol: GTPBP3
• NCBI Official Synonym Symbols: MSS1; MTGP1; THDF1; GTPBG3; COXPD23
• NCBI Protein Information: tRNA modification GTPase GTPBP3, mitochondrial
• UniProt Protein Name: tRNA modification GTPase GTPBP3, mitochondrial
• Protein Family: tRNA modification GTPase
• UniProt Gene Name: GTPBP3
• UniProt Synonym Gene Names: MTGP1
• UniProt Entry Name: GTPB3_HUMAN

NCBI Description

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]