Western Blot (WB)
(GTF2A1L Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GTF2A1L antibody detected the GTF2A1L protein (arrow).)
Rabbit GTF2A1L Polyclonal Antibody | anti-GTF2A1L antibody
GTF2A1L Antibody (C-term)
Western Blot (WB)
(GTF2A1L Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GTF2A1L antibody detected the GTF2A1L protein (arrow).)
Western Blot (WB)
(GTF2A1L Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GTF2A1L antibody detected the GTF2A1L protein (arrow).)
transcription pre-initiation complex on a eukaryotic core promoter
involve the effects of TFIIA on the interaction between
TATA-binding protein (TBP) and DNA. This gene encodes a germ
cell-specific counterpart of the large (alpha/beta) subunit of
general transcription factor TFIIA that is able to stabilize the
binding of TBP to DNA and may be uniquely important to testis
biology. Alternative splicing for this locus has been observed and
two variants, encoding distinct isoforms, have been identified.
Co-transcription of this gene and the neighboring upstream gene
generates a rare transcript (SALF), which encodes a fusion protein
comprised of sequence sharing identity with each individual gene
product.
Kim, M., et al. J. Biol. Chem. 281(45):34288-34298(2006)
Howe, M.L., et al. Stem Cells Dev. 15(2):175-190(2006)
Huang, M., et al. Int. J. Mol. Med. 17(4):599-604(2006)
Upadhyaya, A.B., et al. J. Biol. Chem. 277(37):34208-34216(2002)
NCBI and Uniprot Product Information
NCBI Description
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]
Uniprot Description
GTF2A1L: May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription. Belongs to the TFIIA subunit 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 2p16.3
Cellular Component: cytoplasm; transcription factor TFIIA complex
Molecular Function: DNA binding; transcription coactivator activity
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; cognition
Research Articles on GTF2A1L
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Product Notes
The GTF2A1L gtf2a1l (Catalog #AAA9213791) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 399-428. The GTF2A1L Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's GTF2A1L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GTF2A1L gtf2a1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTF2A1L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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