Western Blot (WB)
(Western blot analysis of GTD2A Antibody (C-term) in K562 cell line lysates (35ug/lane). GTD2A (arrow) was detected using the purified Pab.)
Rabbit anti-Human GTD2A Polyclonal Antibody | anti-GTF2IRD2 antibody
GTD2A Antibody (C-term)
Western Blot (WB)
(Western blot analysis of GTD2A Antibody (C-term) in K562 cell line lysates (35ug/lane). GTD2A (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of GTD2A Antibody (C-term) in K562 cell line lysates (35ug/lane). GTD2A (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(GTD2A Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(GTD2A Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Makeyev, A.V., et al. Proc. Natl. Acad. Sci. U.S.A. 101(30):11052-11057(2004)
Tipney, H.J., et al. Eur. J. Hum. Genet. 12(7):551-560(2004)
NCBI and Uniprot Product Information
NCBI Description
This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
GTF2IRD2: GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the TFII-I family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: nucleus
Molecular Function: DNA binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Research Articles on GTF2IRD2
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Product Notes
The GTF2IRD2 gtf2ird2 (Catalog #AAA9213025) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 812-841. The GTD2A Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GTD2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the GTF2IRD2 gtf2ird2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTD2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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