Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046152 at dilution 1:100)
Rabbit anti-Human GSTZ1 Polyclonal Antibody | anti-GSTZ1 antibody
GSTZ1 Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046152 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046152 at dilution 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2015]
Uniprot Description
GSTZ1: Bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4- nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T- butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. Belongs to the GST superfamily. Zeta family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.5.1.18; Amino Acid Metabolism - tyrosine; Oxidoreductase; Other Amino Acids Metabolism - glutathione; EC 5.2.1.2; Xenobiotic Metabolism - metabolism by cytochrome P450; Isomerase; Mitochondrial
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: cytosol; mitochondrion
Molecular Function: glutathione peroxidase activity; glutathione transferase activity; maleylacetoacetate isomerase activity; protein binding; protein homodimerization activity
Biological Process: glutathione metabolic process; L-phenylalanine catabolic process
Research Articles on GSTZ1
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Product Notes
The GSTZ1 gstz1 (Catalog #AAA7046152) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GSTZ1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GSTZ1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the GSTZ1 gstz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSTZ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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