SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: LO2 and 293T cell lysates, Primary antibody:GSDMA Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes)
Rabbit anti-Human, Mouse GSDMA Polyclonal Antibody | anti-GSDMA antibody
GSDMA Antibody
Gene Names
GSDMA; GSDM; FKSG9; GSDM1
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
GSDMA; Polyclonal Antibody; GSDMA Antibody; GSDM; FKSG9; GSDM1; anti-GSDMA antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-GSDMA antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:100-1:200
IHC: 1:100-1:200
Immunogen
Fusion protein of human GSDMA
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: LO2 and 293T cell lysates, Primary antibody:GSDMA Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes)
SDS-Page
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: LO2 and 293T cell lysates, Primary antibody:GSDMA Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using (GSibody) at dilution 1/115.)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using (GSibody) at dilution 1/115.)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (GSibody) at dilution 1/115.)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (GSibody) at dilution 1/115.)
Related Product Information for anti-GSDMA antibody
May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4, 5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
Product Categories/Family for anti-GSDMA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
49,365 Da
NCBI Official Full Name
Homo sapiens gasdermin A, mRNA
NCBI Official Synonym Full Names
gasdermin A
NCBI Official Symbol
GSDMA
NCBI Official Synonym Symbols
GSDM; FKSG9; GSDM1
NCBI Protein Information
gasdermin-A
UniProt Protein Name
Inositol polyphosphate 5-phosphatase K
Protein Family
UniProt Gene Name
INPP5K
UniProt Synonym Gene Names
PPS; SKIP
UniProt Entry Name
INP5K_HUMAN
Research Articles on GSDMA
Similar Products
Product Notes
The GSDMA inpp5k (Catalog #AAA9434772) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GSDMA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GSDMA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the GSDMA inpp5k for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSDMA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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