Rabbit Groucho 3 Polyclonal Antibody | anti-gro antibody
Groucho 3 (TLE3, ESG3, Transcription Factor)
Gene Names
gro; anon-WO0118547.385; BcDNA.LD33829; BcDNA:LD33829; BEST:GM01575; BEST:LD15161; CG8384; dAES1; dAES2; dGro; DGro; DmelCG8384; E(spl)-WD; E(spl)gro; E(spl)m9/m10; E(spl)[2]; En-spl; Grg/TLE; Gro; GRO; Groucho; l(3)gro; m10; m9; m9-m10; m9/10; m9/m10
Reactivity
Human, Rodent
Applications
ELISA
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
Groucho 3; Polyclonal Antibody; Groucho 3 (TLE3; ESG3; Transcription Factor); Anti -Groucho 3 (TLE3; anti-gro antibody
Host
Rabbit
Reactivity
Human, Rodent
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Groucho 3 / TLE3 / ESG3 transcription factor. Species Crossreactivity: rodent.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, sodium azide, before the addition of glycerol to 40%.
Applicable Applications for anti-gro antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA (titer): 1:200,000.
Dilution: ELISA (titer): 1:200,000.
Immunogen
Synthetic peptide, aa 295-311 STPSSKTKDLGHNDKKSS corresponding to human Groucho 3 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer
Product Categories/Family for anti-gro antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
83.4kD.
NCBI Official Full Name
groucho, isoform I
NCBI Official Synonym Full Names
groucho
NCBI Official Symbol
gro
NCBI Official Synonym Symbols
anon-WO0118547.385; BcDNA.LD33829; BcDNA:LD33829; BEST:GM01575; BEST:LD15161; CG8384; dAES1; dAES2; dGro; DGro; DmelCG8384; E(spl)-WD; E(spl)gro; E(spl)m9/m10; E(spl)[2]; En-spl; Grg/TLE; Gro; GRO; Groucho; l(3)gro; m10; m9; m9-m10; m9/10; m9/m10
NCBI Protein Information
CG8384 gene product from transcript CG8384-RH; CG8384-PA; CG8384-PB; CG8384-PC; CG8384-PD; CG8384-PE; CG8384-PF; CG8384-PG; CG8384-PH; CG8384-PI; dgroucho; gro-PA; gro-PB; gro-PC; gro-PD; gro-PE; gro-PF; gro-PG; gro-PH; gro-PI
UniProt Protein Name
Protein groucho
Protein Family
UniProt Gene Name
gro
UniProt Synonym Gene Names
E(spl)m9/m10; E(spl)m9/10
UniProt Entry Name
GROU_DROME
Uniprot Description
Function: Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta. Ref.5
Subunit structure: Forms a complex with the hairy/Enhancer of split/deadpan family of basic helix-loop-helix proteins in order to repress transcription. Its activity in regulating transcription depends on other proteins as it lacks a DNA-binding motif.
Subcellular location: Nucleus.
Developmental stage: Expressed both maternally and zygotically. Ref.5
Post-translational modification: Ubiquitinated by XIAP/BIRC4. Ref.7
Sequence similarities: Belongs to the WD repeat Groucho/TLE family.Contains 7 WD repeats.
Research Articles on gro
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Product Notes
The gro gro (Catalog #AAA615920) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Groucho 3 (TLE3, ESG3, Transcription Factor) reacts with Human, Rodent and may cross-react with other species as described in the data sheet. AAA Biotech's Groucho 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA (titer): 1:200,000. Researchers should empirically determine the suitability of the gro gro for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Groucho 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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