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Rabbit GRO BETA/MIP-2 Polyclonal Antibody | anti-Cxcl2 antibody

RABBIT ANTI RAT GRO BETA/MIP-2

Gene Names
Cxcl2; Mip-2; Scyb2
Applications
ELISA, Functional Assay, Western Blot
Synonyms
GRO BETA/MIP-2; Polyclonal Antibody; RABBIT ANTI RAT GRO BETA/MIP-2; anti-Cxcl2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - lyophilised
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
100
Applicable Applications for anti-Cxcl2 antibody
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
Application Notes
ELISA: Maximum Dilution: 0.5ug/ml;
Functional Assays: Minimum Dilution: 3.0ug/ml; Maximum Dilution: 5.0ug/ml;
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml
Reconstitution
Reconstitute with 0.1 ml distilled water. The addition of 0.09% sodium azide is recommended for long term storage.N.B. For functional studies do not add sodium azide.
Immunogen
Recombinant rat GRO beta/MIP-2
Buffer Solution
Antiserum Preparation
Antisera to rat GRO beta/MIP-2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Target Species
Rat
Preparation and Storage
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Related Product Information for anti-Cxcl2 antibody
Rabbit anti Rat GRO beta/MIP-2 antibody recognizes rat GRO beta/MIP-2, also known CXCL2, an 8kD chemokine which promotes neutrophil chemotaxis and degranulation and is expressed by monocytes, fibroblasts, endothelial cells, synovial cell and several tumour cell lines.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,783 Da
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 2
NCBI Official Symbol
Cxcl2
NCBI Official Synonym Symbols
Mip-2; Scyb2
NCBI Protein Information
C-X-C motif chemokine 2; CINC-3; MIP2; cytokine-induced neutrophil chemoattractant 3; macrophage inflammatory protein 2; small inducible cytokine subfamily, member 2
UniProt Protein Name
C-X-C motif chemokine 2
Protein Family
UniProt Gene Name
Cxcl2
UniProt Synonym Gene Names
Cinc3; Mip-2; Mip2; Scyb2; CINC-3; MIP2
UniProt Entry Name
CXCL2_RAT

NCBI Description

chemokine involved in the pulmonary inflammatory response [RGD, Feb 2006]

Uniprot Description

CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Cellular Component: extracellular space

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: neutrophil chemotaxis; wound healing; leukocyte chemotaxis; response to amphetamine; response to glucocorticoid stimulus; positive regulation of leukocyte chemotaxis; response to estradiol stimulus; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to heat; response to molecule of bacterial origin; response to gamma radiation; immune response; inflammatory response

Research Articles on Cxcl2

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Product Notes

The Cxcl2 cxcl2 (Catalog #AAA221290) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GRO BETA/MIP-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assays (FN), Western Blot (WB). ELISA: Maximum Dilution: 0.5ug/ml; Functional Assays: Minimum Dilution: 3.0ug/ml; Maximum Dilution: 5.0ug/ml; Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 0.2ug/ml. Researchers should empirically determine the suitability of the Cxcl2 cxcl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRO BETA/MIP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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