Goat GRIPAP1 / GRASP1 Polyclonal Antibody | anti-GRIPAP1 antibody

Goat Polyclonal to Human GRIPAP1 / GRASP1

Cat. Num. AAA244657

• Gene Names: GRIPAP1; GRASP-1
• Reactivity: Gibbon, Gorilla, Human; Predicted Reactivity: Monkey, Rabbit (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: GRIPAP1 / GRASP1; Polyclonal Antibody; Goat Polyclonal to Human GRIPAP1 / GRASP1; Anti-GRIPAP1 / GRASP1 Antibody (N-Terminus) IHC-plus; GRIPAP1; GRIP1 associated protein 1; KIAA1167; GRASP1; MPMGp800B12492Q3; GRASP-1; GRIP1-associated protein 1; Human GRIPAP1; anti-GRIPAP1 antibody

• Host: Goat
• Reactivity: Gibbon, Gorilla, Human; Predicted Reactivity: Monkey, Rabbit (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human GRIPAP1 / GRASP1. This antibody is expected to recognize both reported isoforms (as represented by NP_064522.3; NP_997555.1)
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 841

• Applicable Applications for anti-GRIPAP1 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:32000), IHC-P (3.75 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic peptide LREQTTGLAAELQ-C from the N-terminus of human GRIPAP1 / GRASP1 (NP_064522.3; NP_997555.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant (100%); Marmoset, Rabbit (92%); Bovine (85%).
• Immunogen Type: Synthetic peptide
• Immunogen: GRIPAP1 / GRASP1 antibody was raised against synthetic peptide LREQTTGLAAELQ-C from the N-terminus of human GRIPAP1 / GRASP1 (NP_064522.3; NP_997555.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant (100%); Marmoset, Rabbit (92%); Bovine (85%).
• Antigen Modification: N-Terminus
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-GRIPAP1 / GRASP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC)

(Anti-GRIPAP1 / GRASP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 46592991
• NCBI GeneID: 56850
• NCBI Accession #: NP_064522.3
• NCBI GenBank Nucleotide #: NM_020137.4
• UniProt Accession #: Q4V328; Q3MJ75; Q4V327; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3; A6NL78
• Molecular Weight: 92,738 Da
• NCBI Official Full Name: GRIP1-associated protein 1
• NCBI Official Synonym Full Names: GRIP1 associated protein 1
• NCBI Official Symbol: GRIPAP1
• NCBI Official Synonym Symbols: GRASP-1
• NCBI Protein Information: GRIP1-associated protein 1
• UniProt Protein Name: GRIP1-associated protein 1
• Protein Family: GRIP1-associated protein
• UniProt Gene Name: GRIPAP1
• UniProt Synonym Gene Names: KIAA1167; GRASP-1
• UniProt Entry Name: GRAP1_HUMAN

NCBI Description

This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013]

Uniprot Description

GRIPAP1: a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.[provided by RefSeq, Nov 2009]

Protein type: GEFs, Ras; GEFs

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: early endosome