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Western Blot (WB) (GRINA Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GRINA antibody detected the GRINA protein (arrow).)

Rabbit anti-Human GRINA Polyclonal Antibody | anti-GRINA antibody

GRINA, ID (GRINA, LFG1, NMDARA1, TMBIM3, Protein lifeguard 1, Glutamate [NMDA] receptor-associated protein 1, NMDA receptor glutamate-binding subunit, Putative MAPK-activating protein PM02, Transmembrane BAX inhibitor motif-containing protein 3) (PE)

Gene Names
GRINA; LFG1; HNRGW; TMBIM3; NMDARA1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
GRINA; Polyclonal Antibody; ID (GRINA; LFG1; NMDARA1; TMBIM3; Protein lifeguard 1; Glutamate [NMDA] receptor-associated protein 1; NMDA receptor glutamate-binding subunit; Putative MAPK-activating protein PM02; Transmembrane BAX inhibitor motif-containing protein 3) (PE); Transmembrane BAX inhibitor motif-containing protein 3; anti-GRINA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-GRINA antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
GRINA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the Central region of human GRINA.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GRINA Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GRINA antibody detected the GRINA protein (arrow).)

Western Blot (WB) (GRINA Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GRINA antibody detected the GRINA protein (arrow).)

Immunohistochemistry (IHC)

(GRINA Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRINA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (GRINA Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRINA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-GRINA antibody
References
Zhou, J., et al. Comput Biol Chem 32(3):159-162(2008). Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005). Matsuda, A., et al. Oncogene 22(21):3307-3318(2003). Lewis, T.B., et al. Genomics 32(1):131-133(1996). Collins, C., et al. Genomics 17(1):237-239(1993).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,203 Da
NCBI Official Full Name
protein lifeguard 1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
NCBI Official Symbol
GRINA
NCBI Official Synonym Symbols
LFG1; HNRGW; TMBIM3; NMDARA1
NCBI Protein Information
protein lifeguard 1; putative MAPK-activating protein PM02; NMDA receptor glutamate-binding subunit; glutamate [NMDA] receptor-associated protein 1; transmembrane BAX inhibitor motif containing 3; transmembrane BAX inhibitor motif-containing protein 3; gl
UniProt Protein Name
Protein lifeguard 1
Protein Family
UniProt Gene Name
GRINA
UniProt Synonym Gene Names
LFG1; NMDARA1; TMBIM3
UniProt Entry Name
LFG1_HUMAN

Uniprot Description

NMDARA1: Potential apoptotic regulator. Belongs to the BI1 family. LFG subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: Golgi apparatus; endoplasmic reticulum; integral to membrane

Biological Process: endoplasmic reticulum calcium ion homeostasis

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Product Notes

The GRINA grina (Catalog #AAA6304480) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRINA, ID (GRINA, LFG1, NMDARA1, TMBIM3, Protein lifeguard 1, Glutamate [NMDA] receptor-associated protein 1, NMDA receptor glutamate-binding subunit, Putative MAPK-activating protein PM02, Transmembrane BAX inhibitor motif-containing protein 3) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GRINA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the GRINA grina for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRINA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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