Rabbit anti-Human GRIN2D Polyclonal Antibody | anti-GRIN2D antibody

GRIN2D Antibody

Cat. Num. AAA7045056

• Gene Names: GRIN2D; EB11; NR2D; GluN2D; NMDAR2D
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Antigen Affinity Purified
• Synonyms: GRIN2D; Polyclonal Antibody; GRIN2D Antibody; Glutamate receptor ionotropic; NMDA 2D; GluN2D; EB11; Glutamate [NMDA] receptor subunit epsilon-4; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2D; anti-GRIN2D antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1336

• Applicable Applications for anti-GRIN2D antibody: ELISA (EIA), Western Blot (WB)
• Species: Human
• Immunogen: Recombinant human Glutamate receptor ionotropic, NMDA 2D protein (330-480AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31553 / sc-31551 / sc-1471 / sc-10727
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: GRIN2D antibody IgG at 3.65ug/ml+ HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 144 kDaObserved band size: 144 kDa)

Related Product Information for anti-GRIN2D antibody

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

NCBI and Uniprot Product Information

• NCBI GI #: 153946391
• NCBI GeneID: 2906
• NCBI Accession #: NP_000827.2
• NCBI GenBank Nucleotide #: NM_000836.2
• UniProt Accession #: O15399
• Molecular Weight: 143,752 Da
• NCBI Official Full Name: glutamate receptor ionotropic, NMDA 2D
• NCBI Official Synonym Full Names: glutamate ionotropic receptor NMDA type subunit 2D
• NCBI Official Symbol: GRIN2D
• NCBI Official Synonym Symbols: EB11; NR2D; GluN2D; NMDAR2D
• NCBI Protein Information: glutamate receptor ionotropic, NMDA 2D
• UniProt Protein Name: Glutamate receptor ionotropic, NMDA 2D
• Protein Family: Glutamate receptor ionotropic
• UniProt Gene Name: GRIN2D
• UniProt Synonym Gene Names: GluN2D; NMDAR2D; GluN2D; NMDAR2D; NR2D
• UniProt Entry Name: NMDE4_HUMAN

NCBI Description

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]

Uniprot Description

NMDAR2D: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: N-methyl-D-aspartate selective glutamate receptor complex; plasma membrane

Molecular Function: N-methyl-D-aspartate selective glutamate receptor activity; protein binding; Ras guanyl-nucleotide exchange factor activity

Biological Process: MAPKKK cascade; synaptic transmission