Rabbit GRIM-19 Polyclonal Antibody | anti-MEE4 antibody
GRIM-19 Polyclonal Antibody
Gene Names
MEE4; maternal effect embryo arrest 4; MEE4; T1G11.12; T1G11_12
Applications
Immunoblot, Western Blot
Synonyms
GRIM-19; Polyclonal Antibody; GRIM-19 Polyclonal Antibody; anti-MEE4 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
GRIM-19 [This rabbit antibody recognizes human GRIM-19 (Genes associated with Retinoid-IFN-induced Mortality), a nuclear protein that functions as a cell death regulatory molecule]
This antibody recognizes human GRIM- 19 (Genes associated with Retinoid- IFN-induced Mortality), a nuclear protein that functions as a cell death regulatory molecule. Antisense expression of GRIM-19 confers a strong resistance to IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA.
This antibody recognizes human GRIM- 19 (Genes associated with Retinoid- IFN-induced Mortality), a nuclear protein that functions as a cell death regulatory molecule. Antisense expression of GRIM-19 confers a strong resistance to IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA.
Form/Format
100 ug IgG in 100 ul PBS, pH7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-MEE4 antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approx. 16 kD is detected.
Antigen
Recombinant human GRIM-19 protein
Stabilizer
None
Preservatives
0.02% sodium azide
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Product Categories/Family for anti-MEE4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,126 Da
NCBI Official Full Name
GRIM-19 protein
NCBI Official Symbol
MEE4
NCBI Official Synonym Symbols
maternal effect embryo arrest 4; MEE4; T1G11.12; T1G11_12
NCBI Protein Information
GRIM-19 protein
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-A
Protein Family
UniProt Gene Name
MEE4
UniProt Entry Name
NDADA_ARATH
Uniprot Description
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Subunit structure: Complex I is composed of at least 49 different subunits.
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side
Sequence similarities: Belongs to the complex I NDUFA13 subunit family.
Sequence caution: The sequence AAB80637.1 differs from that shown. Reason: Erroneous gene model prediction.
Similar Products
Product Notes
The MEE4 mee4 (Catalog #AAA194249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GRIM-19 can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. A band of approx. 16 kD is detected. Researchers should empirically determine the suitability of the MEE4 mee4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRIM-19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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