Rabbit anti-Human GRIA3 Polyclonal Antibody | anti-GRIA3 antibody

GRIA3, NT (GRIA3, GLUR3, GLURC, Glutamate receptor 3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3) (FITC)

Cat. Num. AAA6304341

• Gene Names: GRIA3; GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GRIA3; Polyclonal Antibody; NT (GRIA3; GLUR3; GLURC; Glutamate receptor 3; AMPA-selective glutamate receptor 3; GluR-C; GluR-K3; Glutamate receptor ionotropic; AMPA 3) (FITC); AMPA 3; anti-GRIA3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 894

• Applicable Applications for anti-GRIA3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GRIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-217 amino acids from the N-terminal region of human GRIA3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis using MBS6010908 in WiDr cell line lysates (35ug/lane). This demonstrates the GRIA3 antibody detected the GRIA3 protein (arrow).)

Related Product Information for anti-GRIA3 antibody

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Product Categories/Family for anti-GRIA3 antibody

Antibodies; Receptors

References

Ripka, S., et al. Neoplasia 12(8):659-667(2010). Liu, Q., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26(4):376-378(2010). Feyissa, A.M., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(2):279-283(2010). Marek, G.J., et al. Mol. Pharmacol. 77(3):317-326(2010). Formicola, D., et al. BMC Med. Genet. 11, 103 (2010).

NCBI and Uniprot Product Information

• NCBI GI #: 163659856
• NCBI GeneID: 2892
• NCBI Accession #: NP_015564.4; NP_000819.3
• NCBI GenBank Nucleotide #: NP_015564.4
• UniProt Accession #: P42263
• NCBI Official Full Name: glutamate receptor 3 isoform 1
• NCBI Official Synonym Full Names: glutamate ionotropic receptor AMPA type subunit 3
• NCBI Official Symbol: GRIA3
• NCBI Official Synonym Symbols: GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3
• NCBI Protein Information: glutamate receptor 3
• UniProt Protein Name: Glutamate receptor 3
• Protein Family: Glutamate receptor
• UniProt Gene Name: GRIA3
• UniProt Synonym Gene Names: GLUR3; GLURC; GluR-3; GluA3
• UniProt Entry Name: GRIA3_HUMAN

NCBI Description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]