Rabbit anti-Human Granulocyte Macrophage Colony Stimulating Factor Polyclonal Antibody | anti-GM-CSF antibody
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, CSF Alpha, Eosinophil Colony Stimulating Factor, Granulocyte Macrophage Colony Stimulating Factor, Molgramostin, Pluripoietin Alpha, Sa
Gene Names
Csf2; CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Reactivity
Human
Applications
Western Blot, Neutralization Assay, ELISA
Purity
Purified by Immunoaffinity chromatography.
Synonyms
Granulocyte Macrophage Colony Stimulating Factor; Polyclonal Antibody; Granulocyte Macrophage Colony Stimulating Factor (GM-CSF; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; CSF Alpha; Eosinophil Colony Stimulating Factor; Molgramostin; Pluripoietin Alpha; Sa; anti-GM-CSF antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-GM-CSF antibody
Western Blot (WB), Neutralization, ELISA (EIA)
Application Notes
WB: 0.1-0.2ug/ml (detection limit is 1.5-3.0ng/lane, under either reducing or non-reducing conditions).
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity (1.0ng/ml), a concentration of 0.3-0.5ug/ml of this antibody is required.
Applications are based on unconjugated antibody.
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity (1.0ng/ml), a concentration of 0.3-0.5ug/ml of this antibody is required.
Applications are based on unconjugated antibody.
Immunogen
Highly purified (>98%) recombinant human GM-CSF
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
Product Categories/Family for anti-GM-CSF antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14 kDa (125 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor
NCBI Official Synonym Full Names
colony stimulating factor 2 (granulocyte-macrophage)
NCBI Official Symbol
Csf2
NCBI Official Synonym Symbols
CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
Csf2
UniProt Synonym Gene Names
Csfgm; GM-CSF; CSF
UniProt Entry Name
CSF2_MOUSE
Uniprot Description
GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.
Protein type: Secreted; Cytokine; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region
Molecular Function: growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity
Biological Process: negative regulation of cytolysis; epithelial fluid transport; embryonic placenta development; macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of gene expression; positive regulation of interleukin-23 production; positive regulation of cell proliferation; myeloid dendritic cell differentiation; immune response; positive regulation of DNA replication; regulation of cell proliferation
Research Articles on GM-CSF
Similar Products
Product Notes
The GM-CSF csf2 (Catalog #AAA6478884) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Granulocyte Macrophage Colony Stimulating Factor (GM-CSF, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, CSF Alpha, Eosinophil Colony Stimulating Factor, Granulocyte Macrophage Colony Stimulating Factor, Molgramostin, Pluripoietin Alpha, Sa reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Granulocyte Macrophage Colony Stimulating Factor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Neutralization, ELISA (EIA). WB: 0.1-0.2ug/ml (detection limit is 1.5-3.0ng/lane, under either reducing or non-reducing conditions). Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity (1.0ng/ml), a concentration of 0.3-0.5ug/ml of this antibody is required. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the GM-CSF csf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Granulocyte Macrophage Colony Stimulating Factor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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