Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS769855 (GPX5 antibody) at dilution of 1:50)
Rabbit anti-Human GPX5 Polyclonal Antibody | anti-GPX5 antibody
GPX5 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS769855 (GPX5 antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS769855 (GPX5 antibody) at dilution of 1:50)
Western Blot (WB)
(human testis tissue were subjected to SDS PAGE followed by western blot with MBS769855 (GPX5 antibody) at dilution of 1:200)
Western Blot (WB)
(human testis tissue were subjected to SDS PAGE followed by western blot with MBS769855 (GPX5 antibody) at dilution of 1:200)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2008]
Uniprot Description
GPX5: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Belongs to the glutathione peroxidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - arachidonic acid; Secreted, signal peptide; EC 1.11.1.9; Secreted; Other Amino Acids Metabolism - glutathione; Oxidoreductase
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: extracellular region; extracellular space
Molecular Function: glutathione peroxidase activity
Biological Process: lipid metabolic process; response to reactive oxygen species
Research Articles on GPX5
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Product Notes
The GPX5 gpx5 (Catalog #AAA769855) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPX5 Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPX5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GPX5 gpx5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPX5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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