Western Blot (WB)
((0.1g/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat Gpx1 Polyclonal Antibody | anti-Gpx1 antibody
Goat anti-Gpx1 (mouse aa53-67) Antibody
Western Blot: Approx 22kDa band observed in Rat Kidney and Liver lysates and in Mouse Kidney lysates (calculated MW of 22.3kDa according to NP_032186.2). Recommended concentration: 0.1-0.3ug/ml.
Western Blot (WB)
((0.1g/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.1g/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Uniprot Description
GPX1: Protects the hemoglobin in erythrocytes from oxidative breakdown. Homotetramer. Interacts with MIEN1. Belongs to the glutathione peroxidase family.
Protein type: Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - glutathione; Oxidoreductase; EC 1.11.1.9
Cellular Component: cytoplasm; mitochondrion; nucleus
Molecular Function: glutathione binding; glutathione peroxidase activity; oxidoreductase activity; peroxidase activity; phospholipid-hydroperoxide glutathione peroxidase activity; protein binding; selenium binding; SH3 domain binding
Biological Process: angiogenesis involved in wound healing; apoptosis; blood vessel endothelial cell migration; cell proliferation; cell redox homeostasis; endothelial cell development; fat cell differentiation; glutathione metabolic process; heart contraction; hydrogen peroxide catabolic process; induction of apoptosis by oxidative stress; interaction with symbiont; lipid metabolic process; myoblast proliferation; myotube differentiation; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of inflammatory response to antigenic stimulus; positive regulation of protein kinase B signaling cascade; protein amino acid oxidation; regulation of gene expression, epigenetic; regulation of mammary gland epithelial cell proliferation; regulation of neuron apoptosis; response to gamma radiation; response to hydrogen peroxide; response to hydroperoxide; response to lipid hydroperoxide; response to oxidative stress; response to reactive oxygen species; response to selenium ion; response to symbiotic bacterium; response to toxin; response to wounding; response to xenobiotic stimulus; sensory perception of sound; skeletal muscle fiber development; skeletal muscle regeneration; thermoregulation; triacylglycerol metabolic process; UV protection; vasodilation
Research Articles on Gpx1
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Product Notes
The Gpx1 gpx1 (Catalog #AAA422991) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Gpx1 (mouse aa53-67) Antibody reacts with Tested: Mouse, Rat; Expected from sequence similarity: Mouse, Rat, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's Gpx1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 22kDa band observed in Rat Kidney and Liver lysates and in Mouse Kidney lysates (calculated MW of 22.3kDa according to NP_032186.2). Recommended concentration: 0.1-0.3ug/ml. Researchers should empirically determine the suitability of the Gpx1 gpx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DYTEMNDLQK RLGPR. It is sometimes possible for the material contained within the vial of "Gpx1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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