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Western Blot (WB) (Western blot analysis of GPSN2 expression in A2058 cell lysate, The lane on the left is treated with the antigen-specific peptide.)

Rabbit GPSN2 Polyclonal Antibody | anti-GPSN2 antibody

GPSN2 Antibody

Gene Names
TECR; SC2; TER; GPSN2; MRT14
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
GPSN2; Polyclonal Antibody; GPSN2 Antibody; 2410016D23Rik; A230102P12Rik; AI173355; D17Ertd178e; Glycoprotein synaptic 2; Gpsn2; Neuroprotective protein 13; SC2; Synaptic glycoprotein SC2; Tecr; TER; Trans 2; 3 enoyl CoA reductase; anti-GPSN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GPSN2 antibody detects endogenous levels of total GPSN2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
323
Applicable Applications for anti-GPSN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Endoplasmic Reticulum Membrane; Multipass Membrane Protein.
Tissue Specificity
Expressed in most tissues tested. Highly expressed in skeletal muscle.
Predicted Cross Reactivity
Pig, Bovine, Horse, Dog, Chicken, Xenopus
Similarity
Pig (100%), Bovine (92%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (83%)
Conjugation
Unconjugated

Western Blot (WB)

(Western blot analysis of GPSN2 expression in A2058 cell lysate, The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of GPSN2 expression in A2058 cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-GPSN2 antibody
Function: Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2, 3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subunit Structure: Interacts with ELOVL1 and LASS2.
Post-translational Modifications: Glycosylated.
Similarity: Belongs to the steroid 5-alpha reductase family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 36 kDa
Predicted: 37 kDa
NCBI Official Full Name
very-long-chain enoyl-CoA reductase isoform 2
NCBI Official Synonym Full Names
trans-2,3-enoyl-CoA reductase
NCBI Official Symbol
TECR
NCBI Official Synonym Symbols
SC2; TER; GPSN2; MRT14
NCBI Protein Information
very-long-chain enoyl-CoA reductase
UniProt Protein Name
Very-long-chain enoyl-CoA reductase
UniProt Gene Name
TECR
UniProt Synonym Gene Names
GPSN2; SC2; TER

NCBI Description

This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

Uniprot Description

Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Research Articles on GPSN2

Similar Products

Product Notes

The GPSN2 tecr (Catalog #AAA9603785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPSN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPSN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GPSN2 tecr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPSN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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