Rabbit anti-Human GPR78 Polyclonal Antibody | anti-GPR78 antibody

GPR78, ID (GPR78, G-protein coupled receptor 78)

Cat. Num. AAA6012104

• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: GPR78; Polyclonal Antibody; ID (GPR78; G-protein coupled receptor 78); Anti -GPR78; anti-GPR78 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-GPR78 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: GPR78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human GPR78.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(GPR78 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GPR78 antibody detected the GPR78 protein (arrow).)

Related Product Information for anti-GPR78 antibody

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Product Categories/Family for anti-GPR78 antibody

Antibodies; Abs to G Protein Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 36951034
• NCBI GeneID: 27201
• NCBI Accession #: NP_543009.2
• NCBI GenBank Nucleotide #: NM_080819.4
• UniProt Accession #: Q96P69; Q8NGV3
• Molecular Weight: 39,332 Da
• NCBI Official Full Name: G-protein coupled receptor 78
• NCBI Official Synonym Full Names: G protein-coupled receptor 78
• NCBI Official Symbol: GPR78
• NCBI Protein Information: G-protein coupled receptor 78
• UniProt Protein Name: G-protein coupled receptor 78
• Protein Family: G-protein coupled receptor
• UniProt Gene Name: GPR78
• UniProt Entry Name: GPR78_HUMAN

NCBI Description

The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

GPR78: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein signaling, adenylate cyclase activating pathway