Rabbit GPR61 Polyclonal Antibody | anti-GPR61 antibody

Rabbit Polyclonal to Human GPR61

Cat. Num. AAA240103

• Gene Names: GPR61; BALGR; GPCR3
• Reactivity: Human; Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: GPR61; Polyclonal Antibody; Rabbit Polyclonal to Human GPR61; Anti-GPR61 Antibody (Extracellular Domain) IHC-plus; BALGR; GPCR3; G protein-coupled receptor 61; Human GPR61; anti-GPR61 antibody

• Host: Rabbit
• Reactivity: Human; Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human GPR61. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR124 (44%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 451

• Applicable Applications for anti-GPR61 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA, IHC-P (15 - 30 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic 18 amino acid peptide from 2nd extracellular domain of human GPR61. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (94%); Monkey, Elephant, Panda (89%); Mouse, Rat, Horse, Pig (83%).
• Immunogen Type: Synthetic peptide
• Immunogen: GPR61 antibody was raised against synthetic 18 amino acid peptide from 2nd extracellular domain of human GPR61. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (94%); Monkey, Elephant, Panda (89%); Mouse, Rat, Horse, Pig (83%).
• Antigen Modification: Extracellular Domain
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GPR61 antibody IHC of human brain, caudate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-GPR61 antibody

GPR61 is an Orphan-A GPCR with an unknown ligand.

Product Categories/Family for anti-GPR61 antibody

Family: GPCR; Subfamily: Orphan-A

NCBI and Uniprot Product Information

• NCBI GI #: 57165371
• NCBI GeneID: 83873
• NCBI Accession #: NP_114142.3
• NCBI GenBank Nucleotide #: NM_031936.4
• UniProt Accession #: Q9BZJ8; Q6NWS0; Q8TDV4; Q96PR4; A8K1W2
• Molecular Weight: 49,292 Da
• NCBI Official Full Name: probable G-protein coupled receptor 61
• NCBI Official Synonym Full Names: G protein-coupled receptor 61
• NCBI Official Symbol: GPR61
• NCBI Official Synonym Symbols: BALGR; GPCR3
• NCBI Protein Information: probable G-protein coupled receptor 61; biogenic amine receptor-like GPCR; biogenic amine receptor-like G-protein coupled receptor
• UniProt Protein Name: Probable G-protein coupled receptor 61
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR61
• UniProt Synonym Gene Names: BALGR
• UniProt Entry Name: GPR61_HUMAN

NCBI Description

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008]

Uniprot Description

GPR61: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: plasma membrane; integral to membrane; receptor complex

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway