Rabbit GPR55 Polyclonal Antibody | anti-GPR55 antibody

Rabbit Polyclonal to Human GPR55

Cat. Num. AAA243631

• Gene Names: GPR55; LPIR1
• Reactivity: Gibbon, Gorilla, Human, Monkey
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: GPR55; Polyclonal Antibody; Rabbit Polyclonal to Human GPR55; Anti-GPR55 Antibody (C-Terminus) IHC-plus; G-protein coupled receptor 55; G protein-coupled receptor 55; Human GPR55; anti-GPR55 antibody

• Host: Rabbit
• Reactivity: Gibbon, Gorilla, Human, Monkey
• Clonality: Polyclonal
• Specificity: Human GPR55. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 319

• Applicable Applications for anti-GPR55 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (2 - 4 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic 20 amino acid peptide from C-terminus of human GPR55. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Panda (85%); Marmoset, Bovine, Elephant, Horse (80%).
• Immunogen Type: Synthetic peptide
• Immunogen: GPR55 antibody was raised against synthetic 20 amino acid peptide from C-terminus of human GPR55. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Panda (85%); Marmoset, Bovine, Elephant, Horse (80%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GPR55 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR55 antibody IHC of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR55 antibody IHC of human prostate, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GPR55 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-GPR55 antibody

GPR55 is an Orphan-A GPCR with an unknown ligand.

Product Categories/Family for anti-GPR55 antibody

Family: GPCR; Subfamily: Orphan-A

NCBI and Uniprot Product Information

• NCBI GI #: 33695107
• NCBI GeneID: 9290
• NCBI Accession #: NP_005674.2
• NCBI GenBank Nucleotide #: NM_005683.3
• UniProt Accession #: Q9Y2T6; Q8N580
• Molecular Weight: 36,637 Da
• NCBI Official Full Name: G-protein coupled receptor 55
• NCBI Official Synonym Full Names: G protein-coupled receptor 55
• NCBI Official Symbol: GPR55
• NCBI Official Synonym Symbols: LPIR1
• NCBI Protein Information: G-protein coupled receptor 55
• UniProt Protein Name: G-protein coupled receptor 55
• Protein Family: G-protein coupled receptor
• UniProt Gene Name: GPR55
• UniProt Entry Name: GPR55_HUMAN

NCBI Description

This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013]

Uniprot Description

GPR55: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; cannabinoid receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of osteoclast differentiation; phospholipase C activation; positive regulation of Rho protein signal transduction; bone resorption