Immunohistochemistry (IHC)
(Anti-GPR21 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit GPR21 Polyclonal Antibody | anti-GPR21 antibody
Rabbit Polyclonal to Human GPR21
Reactivity
Gibbon, Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GPR21; Polyclonal Antibody; Rabbit Polyclonal to Human GPR21; Anti-GPR21 Antibody (C-Terminus) IHC-plus; G protein-coupled receptor 21; Human GPR21; anti-GPR21 antibody
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Clonality
Polyclonal
Specificity
Human GPR21. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MLL3 (50%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
349
Applicable Applications for anti-GPR21 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human GPR21. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Rat (88%); Mouse, Pig, Bovine, Bat (81%).
Immunogen Type
Synthetic peptide
Immunogen
GPR21 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human GPR21. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Rat (88%); Mouse, Pig, Bovine, Bat (81%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-GPR21 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPR21 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GPR21 antibody
GPR21 is an Orphan-A GPCR with an unknown ligand.
Product Categories/Family for anti-GPR21 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,515 Da
NCBI Official Full Name
probable G-protein coupled receptor 21
NCBI Official Synonym Full Names
G protein-coupled receptor 21
NCBI Official Symbol
GPR21
NCBI Protein Information
probable G-protein coupled receptor 21
UniProt Protein Name
Probable G-protein coupled receptor 21
Protein Family
UniProt Gene Name
GPR21
UniProt Entry Name
GPR21_HUMAN
NCBI Description
This gene encodes a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium. [provided by RefSeq, Nov 2012]
Uniprot Description
GPR21: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q33
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of insulin receptor signaling pathway; positive regulation of multicellular organism growth; glucose homeostasis
Similar Products
Product Notes
The GPR21 gpr21 (Catalog #AAA240001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPR21 reacts with Gibbon, Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPR21 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the GPR21 gpr21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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