Western Blot (WB)
(Western blot (WB) analysis of NDRG3 polyclonal antibody at 1:500 dilutionLaneA: The brain tissue lysate of Mouse)
Rabbit anti-Human, Mouse GPR181 Polyclonal Antibody | anti-GPR181 antibody
GPR181 polyclonal antibody
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
Synonyms
GPR181; Polyclonal Antibody; GPR181 polyclonal antibody; Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3; anti-GPR181 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
NDRG3 polyclonal antibody detects endogenous levels of NDRG3 protein.
Purity/Purification
The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-GPR181 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500~1000
Immunogen
Synthetic peptide, corresponding to Human NDRG3
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -25 degree C long term. Avoid freeze-thaw cycles.
Western Blot (WB)
(Western blot (WB) analysis of NDRG3 polyclonal antibody at 1:500 dilutionLaneA: The brain tissue lysate of Mouse)
Western Blot (WB)
(Western blot (WB) analysis of NDRG3 polyclonal antibody at 1:500 dilutionLaneA: The brain tissue lysate of Mouse)
Related Product Information for anti-GPR181 antibody
The NDRG (N-Myc downstream-regulated gene) family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis. NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice. Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors. Members of the NDRG family each have distinct expression patterns; NDRG3 is most highly expressed in the testis, prostate, ovary, and brain. NDRG3 has also been shown to be up-regulated by androgen in prostate cell lines and can promote cell growth in those cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,409 Da
NCBI Official Full Name
protein NDRG3 isoform b
NCBI Official Synonym Full Names
NDRG family member 3
NCBI Official Symbol
NDRG3
NCBI Protein Information
protein NDRG3; N-myc downstream-regulated gene 3 protein
UniProt Protein Name
Protein NDRG3
UniProt Gene Name
NDRG3
UniProt Entry Name
NDRG3_HUMAN
Uniprot Description
NDRG3: sequence is similar to alpha/beta hydrolases. During development, NDRG3 is expressed at high levels in the spinal cord and the thymic rudiment. NDRG3 is located throughout the mouse cerebrum and cerebellum. NDRG1 and NDRG3 belong to a subfamily, and NDRG2 and NDRG4 to another. In humans, NDRG3 is highly expressed in brain and testis. Unlike Ndr1, Ndr2 and Ndr3 appear not to be controlled by N-myc or c-myc. Three alternately spliced human isoforms have been reported.
Protein type: Cell development/differentiation
Chromosomal Location of Human Ortholog: 20q11.21-q11.23
Cellular Component: cytoplasm
Biological Process: spermatogenesis; negative regulation of cell growth; cell differentiation
Research Articles on GPR181
Similar Products
Product Notes
The GPR181 ndrg3 (Catalog #AAA3014871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPR181 polyclonal antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GPR181 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500~1000. Researchers should empirically determine the suitability of the GPR181 ndrg3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR181, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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